现代医药卫生
現代醫藥衛生
현대의약위생
MODERN MEDICINE HEALTH
2015年
8期
1137-1139
,共3页
乳腺肿瘤/放射疗法%黄芪%片剂%人参%生活质量
乳腺腫瘤/放射療法%黃芪%片劑%人參%生活質量
유선종류/방사요법%황기%편제%인삼%생활질량
Breast neoplasms/radiotherapy%Astragalus membranaceus%Tablets%Ginseng%Quality of life
目的:观察十一味参芪片在乳腺癌放疗中的辅助作用。方法选择2013年10月至2014年4月四川省人民医院肿瘤科收治的乳腺癌患者42例,随机分为治疗组22例和对照组20例。治疗组在放疗同时口服十一味参芪片,对照组行常规放疗。观察患者疗效、体质量变化、生活质量、放射性皮肤损伤、血液学毒性反应发生情况。结果治疗组与对照组疗效、放射性皮肤损伤比较,差异均无统计学意义(P>0.05)。治疗组患者体质量增加及稳定率[90.9%(20/22)]、生活质量提高及稳定率[90.9%(20/22)]均高于对照组[分别为65.0%(13/20)、70.0%(14/20)],差异均有统计学意义(P<0.05)。治疗组及对照组白细胞减少(≥Ⅱ度)发生率分别为36.4%(8/22)、70.0%(14/20),血小板减少(≥Ⅱ度)发生率分别为22.7%(5/22)、45.0%(9/20),两组比较,差异均有统计学意义(P<0.05)。结论十一味参芪片能减轻放疗血液学毒性反应,提高患者一般状况及放疗耐受性,改善其生活质量。
目的:觀察十一味參芪片在乳腺癌放療中的輔助作用。方法選擇2013年10月至2014年4月四川省人民醫院腫瘤科收治的乳腺癌患者42例,隨機分為治療組22例和對照組20例。治療組在放療同時口服十一味參芪片,對照組行常規放療。觀察患者療效、體質量變化、生活質量、放射性皮膚損傷、血液學毒性反應髮生情況。結果治療組與對照組療效、放射性皮膚損傷比較,差異均無統計學意義(P>0.05)。治療組患者體質量增加及穩定率[90.9%(20/22)]、生活質量提高及穩定率[90.9%(20/22)]均高于對照組[分彆為65.0%(13/20)、70.0%(14/20)],差異均有統計學意義(P<0.05)。治療組及對照組白細胞減少(≥Ⅱ度)髮生率分彆為36.4%(8/22)、70.0%(14/20),血小闆減少(≥Ⅱ度)髮生率分彆為22.7%(5/22)、45.0%(9/20),兩組比較,差異均有統計學意義(P<0.05)。結論十一味參芪片能減輕放療血液學毒性反應,提高患者一般狀況及放療耐受性,改善其生活質量。
목적:관찰십일미삼기편재유선암방료중적보조작용。방법선택2013년10월지2014년4월사천성인민의원종류과수치적유선암환자42례,수궤분위치료조22례화대조조20례。치료조재방료동시구복십일미삼기편,대조조행상규방료。관찰환자료효、체질량변화、생활질량、방사성피부손상、혈액학독성반응발생정황。결과치료조여대조조료효、방사성피부손상비교,차이균무통계학의의(P>0.05)。치료조환자체질량증가급은정솔[90.9%(20/22)]、생활질량제고급은정솔[90.9%(20/22)]균고우대조조[분별위65.0%(13/20)、70.0%(14/20)],차이균유통계학의의(P<0.05)。치료조급대조조백세포감소(≥Ⅱ도)발생솔분별위36.4%(8/22)、70.0%(14/20),혈소판감소(≥Ⅱ도)발생솔분별위22.7%(5/22)、45.0%(9/20),량조비교,차이균유통계학의의(P<0.05)。결론십일미삼기편능감경방료혈액학독성반응,제고환자일반상황급방료내수성,개선기생활질량。
Objective To observe subsidiarity effect of Eleven Shenqi tablets for breast cancer radiotherapy. Methods A total of 42 patients with breast cancer accepted radiotherapy after the operation and chemotherapy from October 2013 to April 2014 were randomly divided into the treatment group (22 cases) and the control group (20 cases). The treatment group was given orally Eleven Shenqi tablets during the radiotherapy while the control group with regular radiotherapy. It was observed the effect , body weight change,quality of life,radiation-induced skin injury and hematologic toxicities. Results Compared with the control group,the effect and radiation-induced skin injury of the treatment group were no statistical significance in difference (P>0.05). The stability rates of body weight increase and life quality in the treatment group were higher than those of the control group [90.9%(20/22),90.9%(20/22) vs. 65.0%(13/20),70.0%(14/20)],whose difference was statistically significant(P<0.05). The incidences of leucopenia(≥Ⅱdegree)in the treatment group and the control group were 36.4%(8/22)and 70.0%(14/20)respectively and thrombocytopenia(≥Ⅱdegree)in the treatment group and the control group were 22.7%(5/22)and 45.0%(9/20) respectively. There were statistical significance in difference(P<0.05). Conclusion Eleven Shenqi tablets have a good effect in decreasing the toxicities of radiotherapy and improving the general condition of the patient ,radiotherapy tolerance and quality of life.