现代医药卫生
現代醫藥衛生
현대의약위생
MODERN MEDICINE HEALTH
2015年
8期
1145-1147
,共3页
心房颤动%心电描记术%磺胺类%伊布利特
心房顫動%心電描記術%磺胺類%伊佈利特
심방전동%심전묘기술%광알류%이포리특
Atrial fibrillation%Electrocardiography%Sulfonamides%Ibutilide
目的：探讨体表心电图频谱分析在预测伊布利特（富马酸伊布利特注射液）治疗心房颤动（简称房颤）疗效中的作用。方法选取2013年10月至2014年3月在该院住院治疗的符合2012年欧洲心脏学会《心房颤动诊疗指南》标准的房颤患者40例，其中11例阵发性房颤患者及29例持续性房颤患者。记录V1导联体表心电图，基于 Mat-lab平台对患者心电图进行QRS-T波去除后频谱分析，并计算主导心房频率（简称主频）。比较不同复律结局的主频。结果使用富马酸伊布利特注射液后成功复律28例，未成功复律12例。阵发性房颤患者的主频值为（4.6±0.5）Hz，持续性房颤患者的主频值为（5.0±0.8）Hz，二者比较，差异有统计学意义（P＜0.01）。所有伊布利特成功复律患者主频值为（4.6±0.6）Hz，未成功复律患者主频值为（5.2±0.7）Hz，二者比较，差异有统计学意义（P＜0.01）。持续性房颤患者中伊布利特成功复律患者主频值为（4.5±0.7）Hz，未成功复律患者主频值为（5.4±0.6）Hz，二者比较，差异有统计学意义（P＜0.01）。结论体表心电图频谱分析可预测伊布利特复律持续性房颤的效果；体表心电图主频大小与房颤的复律结局有关，主频越小，房颤更易于被伊布利特转复。
目的：探討體錶心電圖頻譜分析在預測伊佈利特（富馬痠伊佈利特註射液）治療心房顫動（簡稱房顫）療效中的作用。方法選取2013年10月至2014年3月在該院住院治療的符閤2012年歐洲心髒學會《心房顫動診療指南》標準的房顫患者40例，其中11例陣髮性房顫患者及29例持續性房顫患者。記錄V1導聯體錶心電圖，基于 Mat-lab平檯對患者心電圖進行QRS-T波去除後頻譜分析，併計算主導心房頻率（簡稱主頻）。比較不同複律結跼的主頻。結果使用富馬痠伊佈利特註射液後成功複律28例，未成功複律12例。陣髮性房顫患者的主頻值為（4.6±0.5）Hz，持續性房顫患者的主頻值為（5.0±0.8）Hz，二者比較，差異有統計學意義（P＜0.01）。所有伊佈利特成功複律患者主頻值為（4.6±0.6）Hz，未成功複律患者主頻值為（5.2±0.7）Hz，二者比較，差異有統計學意義（P＜0.01）。持續性房顫患者中伊佈利特成功複律患者主頻值為（4.5±0.7）Hz，未成功複律患者主頻值為（5.4±0.6）Hz，二者比較，差異有統計學意義（P＜0.01）。結論體錶心電圖頻譜分析可預測伊佈利特複律持續性房顫的效果；體錶心電圖主頻大小與房顫的複律結跼有關，主頻越小，房顫更易于被伊佈利特轉複。
목적：탐토체표심전도빈보분석재예측이포리특（부마산이포리특주사액）치료심방전동（간칭방전）료효중적작용。방법선취2013년10월지2014년3월재해원주원치료적부합2012년구주심장학회《심방전동진료지남》표준적방전환자40례，기중11례진발성방전환자급29례지속성방전환자。기록V1도련체표심전도，기우 Mat-lab평태대환자심전도진행QRS-T파거제후빈보분석，병계산주도심방빈솔（간칭주빈）。비교불동복률결국적주빈。결과사용부마산이포리특주사액후성공복률28례，미성공복률12례。진발성방전환자적주빈치위（4.6±0.5）Hz，지속성방전환자적주빈치위（5.0±0.8）Hz，이자비교，차이유통계학의의（P＜0.01）。소유이포리특성공복률환자주빈치위（4.6±0.6）Hz，미성공복률환자주빈치위（5.2±0.7）Hz，이자비교，차이유통계학의의（P＜0.01）。지속성방전환자중이포리특성공복률환자주빈치위（4.5±0.7）Hz，미성공복률환자주빈치위（5.4±0.6）Hz，이자비교，차이유통계학의의（P＜0.01）。결론체표심전도빈보분석가예측이포리특복률지속성방전적효과；체표심전도주빈대소여방전적복률결국유관，주빈월소，방전경역우피이포리특전복。
Objective To approach the role of surface electrocardiogram frequency spectra analysis in effect prediction of atrial fibrillation(AF) treated by Ibutilide. Methods A total of 40 inpatients with AF in conformity with the standard of Guide-line on Diagnosis and Treatment of European Society of Cardiology in 2012 admitted in this hospital from October 2013 to March 2014 were selected and V1 recorded electrocardiography ,11 patients with paroxysmal AF and 29 patients with persistent AF were included. Relying on frequency analysis by Matlab platform on electrocardiogram of patients after removal of QRS-T wave, the dominant AF was calculated(abbreviated as DF). It was compared the DF of the patients with different cardioversion endings. Results After using Ibutilide fumarate injection,28 patients were restored to sinus rhythm successfully and the rest 12 patients failed. The DF values for the patients with paroxysmal AF and with continuous AF were (4.6±0.5)Hz and(5.0±0.8)Hz respectively. There was statistical significance between the two above-mentioned(P<0.01). The DF average value of the patients with successful cardioversion with Ibutilide was(4.5±0.7)Hz and the one with unsuccessful cardioversion was (5.4±0.6)Hz. The two was compared and showed that the difference had statistical significance (P<0.01). Conclusion Body surface electrocardiogram frequency spectra analysis may predict the effect of persistent atrial fibrillation with Ibutilide. The DF size of body surface electrocardiogram is related to the cardioversion ending of AF. The less the DF is ,the easier the AF cardioversion become with Ibutilide.
