CAJ | 학술논문

目的：比较治疗终点(停药)HBsAg定量，分析终点HBsAg定量与普通干扰素治疗慢性乙肝1年内复发的相关性。方法：2009年1月-2013年6月收治慢性乙型肝炎患者90例，分为复发组和无复发组，比较两组停药时HBsAg定量的不同。结果：复发组停药时HBsAg定量较高，两组比较差异具有统计学意义(P＜0.05)。结论：普通干扰素治疗慢性乙肝达到治疗终点时HBsAg定量的高低与停药后1年内复发率存在明显的正相关性。普通干扰素治疗慢性乙型肝炎停药时HBsAg的水平是推断治疗后1年内复发的有效预测指标。
목적：비교치료종점(정약)HBsAg정량，분석종점HBsAg정량여보통간우소치료만성을간1년내복발적상관성。방법：2009년1월-2013년6월수치만성을형간염환자90례，분위복발조화무복발조，비교량조정약시HBsAg정량적불동。결과：복발조정약시HBsAg정량교고，량조비교차이구유통계학의의(P＜0.05)。결론：보통간우소치료만성을간체도치료종점시HBsAg정량적고저여정약후1년내복발솔존재명현적정상관성。보통간우소치료만성을형간염정약시HBsAg적수평시추단치료후1년내복발적유효예측지표。
Objective:To compare the treatment terminal HBsAg quantity and analyze the correlation of terminal HBsAg quantity and the recurrence within 1 year of chronic hepatitis b treated with ordinary interferon.Methods:90 cases of patients with chronic hepatitis b from January 2009 to June 2013 were divided into the relapse group and the no-relapse group and the differences of HBsAg quantity in the two groups were compared.Results:The terminal HBsAg quantity of the relapse group was higher,there was statistically significant difference between the two groups(P<0.05).Conclusion:The terminal HBsAg quantity of chronic hepatitis b treated by ordinary interferon had obviously positive correlation with the recurrence rate within 1 year.The terminal HBsAg quantity of chronic hepatitis b treated by ordinary interferon was inferred effective predictors of recurrence within 1 year after treatment.