中国社区医师
中國社區醫師
중국사구의사
Chinese Community Doctors
2015年
11期
80-81
,共2页
新生儿%高胆红素血症%头颅MR
新生兒%高膽紅素血癥%頭顱MR
신생인%고담홍소혈증%두로MR
Newborn%Hyperbilirubinemia%Cranial MR
目的：研究无胆红素脑病临床症状的新生儿，头颅MR对称性苍白球T1WI高信号改变预后情况。方法：收治新生儿30例，头颅MR有典型特征性改变，所有患者均无明显胆红素脑病典型特征性临床表现。同时排除胆道闭锁、肝炎综合征等直接胆红素升高为主的疾病及先天畸形、遗传代谢病，以及排除颅内感染、颅内出血、缺氧缺血性脑病等疾病患者。对所有患者进行随访观察、神经行为发育检查，并进行相关项目复查。结果：对上述所有患者生后1周岁内随诊观察、神经行为发育检查，神经行为发育情况基本正常。结论：头颅MRI对称性苍白球T1WI高信号改变不能作为高胆红素血症患者胆红素脑病的唯一标准，没有胆红素脑病临床表现，仅有头颅MRI改变的高胆红素血症患者一般不会有神经系统后遗症。
目的：研究無膽紅素腦病臨床癥狀的新生兒，頭顱MR對稱性蒼白毬T1WI高信號改變預後情況。方法：收治新生兒30例，頭顱MR有典型特徵性改變，所有患者均無明顯膽紅素腦病典型特徵性臨床錶現。同時排除膽道閉鎖、肝炎綜閤徵等直接膽紅素升高為主的疾病及先天畸形、遺傳代謝病，以及排除顱內感染、顱內齣血、缺氧缺血性腦病等疾病患者。對所有患者進行隨訪觀察、神經行為髮育檢查，併進行相關項目複查。結果：對上述所有患者生後1週歲內隨診觀察、神經行為髮育檢查，神經行為髮育情況基本正常。結論：頭顱MRI對稱性蒼白毬T1WI高信號改變不能作為高膽紅素血癥患者膽紅素腦病的唯一標準，沒有膽紅素腦病臨床錶現，僅有頭顱MRI改變的高膽紅素血癥患者一般不會有神經繫統後遺癥。
목적：연구무담홍소뇌병림상증상적신생인，두로MR대칭성창백구T1WI고신호개변예후정황。방법：수치신생인30례，두로MR유전형특정성개변，소유환자균무명현담홍소뇌병전형특정성림상표현。동시배제담도폐쇄、간염종합정등직접담홍소승고위주적질병급선천기형、유전대사병，이급배제로내감염、로내출혈、결양결혈성뇌병등질병환자。대소유환자진행수방관찰、신경행위발육검사，병진행상관항목복사。결과：대상술소유환자생후1주세내수진관찰、신경행위발육검사，신경행위발육정황기본정상。결론：두로MRI대칭성창백구T1WI고신호개변불능작위고담홍소혈증환자담홍소뇌병적유일표준，몰유담홍소뇌병림상표현，부유두로MRI개변적고담홍소혈증환자일반불회유신경계통후유증。
Objective:To study the prognosis of cranial MR symmetry pallidum T1W1 high signal change in the newborn without bilirubin encephalopathy clinical manifestations.Methods:30 newborns were selected.Their cranial MR had typical characteristic change,all patients had no clear bilirubin encephalopathy typical characteristic clinical manifestations.At the same time,it excluded biliary atresia,hepatitis syndrome and other direct bilirubin increased disease and congenital malformation,inherited metabolic diseases,and excluded intracranial infection,intracranial hemorrhage,hypoxic ischemic encephalopathy and other neurological diseases.Results:All of these patients were given follow-up observation,neurobehavioral development examination within 1 year,the neurobehavioral development situation was normal.Conclusion:The cranial MR symmetry pallidum T1W1 high signal change cannot be the only standard of bilirubin encephalopathy in patients with hyperbilirubinemia,the patients with hyperbilirubinemia have no clinical manifestations of bilirubin encephalopathy,only have cranial MR change,they do not have the sequelae of nervous system.
