中国社区医师
中國社區醫師
중국사구의사
Chinese Community Doctors
2015年
16期
19-19
,共1页
2型糖尿病%利拉鲁肽%心血管疾病
2型糖尿病%利拉魯肽%心血管疾病
2형당뇨병%리랍로태%심혈관질병
Type 2 diabetes mellitus%Liraglutide%Cardiovascular disease
目的：探讨利拉鲁肽对2型糖尿病患者心血管的保护效果。方法：收治2型糖尿病患者60例，接受二甲双胍+利拉鲁肽治疗，测定患者服药前、服药24周后的空腹血糖(FPG)、餐后2 h 血糖(2 hPG)、糖化血红蛋白(HbA1c)、收缩压(SBP)、舒张压、颈动脉内膜中层厚度(IMT)。结果：相比于治疗前，治疗24周后患者的FPG、2 hPG、HbA1c、SBP、IMT中层厚度均显著降低(P＜0.05)。结论：利拉鲁肽可以平稳地降低血糖，还能通过降压、抗炎等机制保护患者的心脏安全。
目的：探討利拉魯肽對2型糖尿病患者心血管的保護效果。方法：收治2型糖尿病患者60例，接受二甲雙胍+利拉魯肽治療，測定患者服藥前、服藥24週後的空腹血糖(FPG)、餐後2 h 血糖(2 hPG)、糖化血紅蛋白(HbA1c)、收縮壓(SBP)、舒張壓、頸動脈內膜中層厚度(IMT)。結果：相比于治療前，治療24週後患者的FPG、2 hPG、HbA1c、SBP、IMT中層厚度均顯著降低(P＜0.05)。結論：利拉魯肽可以平穩地降低血糖，還能通過降壓、抗炎等機製保護患者的心髒安全。
목적：탐토리랍로태대2형당뇨병환자심혈관적보호효과。방법：수치2형당뇨병환자60례，접수이갑쌍고+리랍로태치료，측정환자복약전、복약24주후적공복혈당(FPG)、찬후2 h 혈당(2 hPG)、당화혈홍단백(HbA1c)、수축압(SBP)、서장압、경동맥내막중층후도(IMT)。결과：상비우치료전，치료24주후환자적FPG、2 hPG、HbA1c、SBP、IMT중층후도균현저강저(P＜0.05)。결론：리랍로태가이평은지강저혈당，환능통과강압、항염등궤제보호환자적심장안전。
Objective:To explore the protective effect of liraglutide on cardiovascular in patients with type 2 diabetes mellitus. Methods:60 patients with type 2 diabetes mellitus were selected.They were treated by metformin plus liraglutide.Before treatment and 24 weeks after medication,fasting blood glucose,postprandial 2 hours blood glucose,glycated hemoglobin,systolic blood pressure,diastolic blood pressure,carotid artery intima-media thickness were measured.Results:Compared with before treatment, at 24 weeks after treatment,fasting blood glucose,postprandial 2 hours blood glucose,glycated hemoglobin,systolic blood pressure, carotid artery intima-media thickness were significantly reduced(P<0.05).Conclusion:Liraglutide can steadily reduce blood sugar.It can protect the cardiac safety through the anti-hypertension,anti-inflammatory mechanism.
