CAJ | 학술논문

目的：探究原发性中枢神经系统淋巴瘤(PCNSL)的CT、MRI诊断结果。方法对2010年5月—2014年5月期间该院收治的52例PCNSL瘤患者的CT和MRI影像学资料进行回顾性分析。结果52例患者中共72个病灶,病灶多分布于大脑半球邻近蛛网膜下腔及脑室周围深部白质,尤其以额叶分布居多；CT平扫呈等或稍高密度,MRI图像显示,T1WI、T2WI以等信号为主；CT和MRI增强扫描,大多肿瘤实质呈均匀性明显强化,肿瘤边缘呈欠楚或不清楚,边缘大多具有“毛刺征”,有不同程度占位及水肿区。术前影像诊断为原发性中枢系统淋巴瘤49例(94.2%),与病理结果比较,差异无统计学意义(＞0.05)。结论临床需早期行影像学检查,并结合临床资料,必要时行立体定向活检,对早期明确诊断PCNSL有重要的临床意义。
목적：탐구원발성중추신경계통림파류(PCNSL)적CT、MRI진단결과。방법대2010년5월—2014년5월기간해원수치적52례PCNSL류환자적CT화MRI영상학자료진행회고성분석。결과52례환자중공72개병조,병조다분포우대뇌반구린근주망막하강급뇌실주위심부백질,우기이액협분포거다；CT평소정등혹초고밀도,MRI도상현시,T1WI、T2WI이등신호위주；CT화MRI증강소묘,대다종류실질정균균성명현강화,종류변연정흠초혹불청초,변연대다구유“모자정”,유불동정도점위급수종구。술전영상진단위원발성중추계통림파류49례(94.2%),여병리결과비교,차이무통계학의의(＞0.05)。결론림상수조기행영상학검사,병결합림상자료,필요시행입체정향활검,대조기명학진단PCNSL유중요적림상의의。
Objective To explore the diagnosis of primary central nervous system lymphoma(PCNSL) by CT and MRI.Methods A retrospective analysis was conducted on the CT and MRI imaging data of 52 cases with PCNSL admitted in our hospital from May 2010 to May 2014.Results Of the 52 cases, a total of 72 lesions were detected, which mostly located in the deep white matter in cerebral hemisphere adjacent subarachnoid space and periventricular, particularly in the frontal lobe. Plain CT scan showed equal or slightly higher density, MRI images showed mainly T1WI, T2WI and other signals; CT and MRI enhanced scan showed that most tumor parenchyma appeared homogenous and significant enhancement, tumor margin was less clear or not clear, and most with “glitches” sign, and there were different degrees of occupancy and edema. 49 cases(94.2%) were diagnosed as PCNSL by the preoperative imaging examination, and there was no significant difference in the findings of preoperative imaging examination with those of pathology(>0.05).Conclusion Imaging examination carried out early in clinical practice combined with the clinical data of the patients and stereotactic biopsy performed if necessary are of great clinical significance in diagnosing PCNSL early and clearly.