CAJ | 학술논문

目的：探讨糖皮质激素在结核性脑膜炎中的治疗效果。方法整群选取该院于2008年1月-2012年12月收治的96例结核性脑膜炎患者为研究对象，随机分为对照组和观察组，对照组采用常规治疗，观察组在常规治疗的基础上配合糖皮质激素。比较两组患者治疗后的转归率和各项指标改善情况。结果观察组良好转归率为72.91豫，高于对照组的43.75豫，差异具有统计学意义(P<0.05)；观察组患者的意识恢复时间、白细胞计数、蛋白质含量等指标改善程度均优于对照组，差异具有统计学意义(P<0.05)。结论对结核性脑膜炎患者采用糖皮质激素配合治疗可以提高良好转归率，提高治疗效果。
목적：탐토당피질격소재결핵성뇌막염중적치료효과。방법정군선취해원우2008년1월-2012년12월수치적96례결핵성뇌막염환자위연구대상，수궤분위대조조화관찰조，대조조채용상규치료，관찰조재상규치료적기출상배합당피질격소。비교량조환자치료후적전귀솔화각항지표개선정황。결과관찰조량호전귀솔위72.91예，고우대조조적43.75예，차이구유통계학의의(P<0.05)；관찰조환자적의식회복시간、백세포계수、단백질함량등지표개선정도균우우대조조，차이구유통계학의의(P<0.05)。결론대결핵성뇌막염환자채용당피질격소배합치료가이제고량호전귀솔，제고치료효과。
Objective To discuss the efficacy of glucocorticoids in the treatment of tuberculous meningitis. Methods Selection of our hospital in January 2008 to December 2012, 96 cases of patients with tuberculous meningitis who were treated betweent Jan-uary 2008 and December 2012 in our hospital were randomly divided into control group and observation group. The conventional treatment was conducted in the control group, while glucocorticoid was used in the observation group on the basis of conventional treatment. Comparison of two groups of patients after treatment outcome rate and improve the indicators. Results Observation group good outcome at a rate of 72.91%, 43.75%higher than that of control group, the results have statistically significant(P<0.05);Ob-servation group of patients with consciousness recovery time, leucocyte computation and protein content improved indicators were superior to control group, the results have of statistical significance (P<0.05). Conclusion Tuberculous meningitis in patients with glucocorticoid therapy can increase the rate of good outcomes, improve the therapeutic effect.