中外医疗
中外醫療
중외의료
CHINA FOREIGN MEDICAL TREATMENT
2015年
12期
87-88
,共2页
曲美他嗪%硝酸异山梨酯%稳定性劳力型心绞痛%临床效果
麯美他嗪%硝痠異山梨酯%穩定性勞力型心絞痛%臨床效果
곡미타진%초산이산리지%은정성로력형심교통%림상효과
Trimetazidine%Isosorbide dinitrate%Stable angina pectoris%Clinical results
目的：探析曲美他嗪与硝酸异山梨酯治疗稳定性劳力型心绞痛效果。方法整群选取该院2012年1月-2014年11月收治的78例稳定性劳力型心绞痛患者，对其临床资料进行回顾性分析，并在患者及家属知情同意的情况下将其分为治疗组和对照组，治疗组给予曲美他嗪，对照组给予硝酸异山梨酯，对比分析两组患者的治疗有效率及患者恢复情况。结果经治疗后，治疗组患者的有效率为97.46%，对照组患者的有效率为84.62%，两者相比较差异显著，P<0.05有统计学意义；两组患者的各项临床指标均有所改善，且治疗组显著优于对照组，P<0.05有统计学意义；治疗组患者的不良反应发生率为7.69%，对照组不良反应反生率为17.95%，两组比较差异有统计学意义(P<0.05)。结论曲美他嗪与硝酸异山梨酯治疗稳定性劳力型心绞痛都有较好的效果，但曲美他嗪能够更好的改善患者心肌缺血的症状，且患者耐受性好，值得应用。
目的：探析麯美他嗪與硝痠異山梨酯治療穩定性勞力型心絞痛效果。方法整群選取該院2012年1月-2014年11月收治的78例穩定性勞力型心絞痛患者，對其臨床資料進行迴顧性分析，併在患者及傢屬知情同意的情況下將其分為治療組和對照組，治療組給予麯美他嗪，對照組給予硝痠異山梨酯，對比分析兩組患者的治療有效率及患者恢複情況。結果經治療後，治療組患者的有效率為97.46%，對照組患者的有效率為84.62%，兩者相比較差異顯著，P<0.05有統計學意義；兩組患者的各項臨床指標均有所改善，且治療組顯著優于對照組，P<0.05有統計學意義；治療組患者的不良反應髮生率為7.69%，對照組不良反應反生率為17.95%，兩組比較差異有統計學意義(P<0.05)。結論麯美他嗪與硝痠異山梨酯治療穩定性勞力型心絞痛都有較好的效果，但麯美他嗪能夠更好的改善患者心肌缺血的癥狀，且患者耐受性好，值得應用。
목적：탐석곡미타진여초산이산리지치료은정성로력형심교통효과。방법정군선취해원2012년1월-2014년11월수치적78례은정성로력형심교통환자，대기림상자료진행회고성분석，병재환자급가속지정동의적정황하장기분위치료조화대조조，치료조급여곡미타진，대조조급여초산이산리지，대비분석량조환자적치료유효솔급환자회복정황。결과경치료후，치료조환자적유효솔위97.46%，대조조환자적유효솔위84.62%，량자상비교차이현저，P<0.05유통계학의의；량조환자적각항림상지표균유소개선，차치료조현저우우대조조，P<0.05유통계학의의；치료조환자적불량반응발생솔위7.69%，대조조불량반응반생솔위17.95%，량조비교차이유통계학의의(P<0.05)。결론곡미타진여초산이산리지치료은정성로력형심교통도유교호적효과，단곡미타진능구경호적개선환자심기결혈적증상，차환자내수성호，치득응용。
Objective To investigate the effects of Trimetazidine and Tsosorbide dinitrate in the treatment of stable exertional angina. Methods Clinical data of 78 patients with stable angina pectoris admitted in our hospital between January 2012 and November 2014 were retrospectively analyzed, and the patients were divided into the treatment group and the control group with the their family's permission. Trimetazidine was used in the treatment group, while isosorbide dinitrate was used in the control group. Effective rate of treatment and recovery condition were compared between the two groups. Results After treatment, effective rate was 97.46%in the treatment group, and 84.62%in the control group, and the differences between the two groups had statisti-cal significance (P<0.05);Clinical indexes in the two groups were better, and they in the treatment group were better than in the control group and the differences were statistically significant(P<0.05);The incidence of adverse reactions was 7.69%in the treat-ment group, while 17.95% in the control group, and the differences were statistically significant (P<0.05). Conclusion Good ef-fects can be found both in Trimetazidine and Isosorbide dinitrate in the treatment of stable exertional angina. Trimetazidine with the function of alleviating myocardial ischemia and better tolerance is more recommenable for clinical application.
