中外医疗
中外醫療
중외의료
CHINA FOREIGN MEDICAL TREATMENT
2015年
12期
5-6
,共2页
充血性心力衰竭%心肌肌钙蛋白T%电化学发光免疫分析法%相关性
充血性心力衰竭%心肌肌鈣蛋白T%電化學髮光免疫分析法%相關性
충혈성심력쇠갈%심기기개단백T%전화학발광면역분석법%상관성
Congestive heart failure%Cardiac troponin T%Electrochemiluminescence immunoassay%Correlation
目的：研究充血性心力衰竭患者(CHF)病人血清心肌肌钙蛋白T(cTNT)升高与否，以及探讨升高程度与心衰严重程度之间的关系。方法该研究选取该院2012年3月-2014年4月期间在该院接受住院治疗的充血性心力衰竭患者65例为研究对象，选择同期门诊体检的健康患者65例为对照组，通过运用电化学发光免疫分析法进行测定。结果两组患者在性别、年龄、学历等人口学特征上均不存在差异，发现研究组cTNT浓度高达(0.172±0.062)ng/mL，而对照组浓度仅为(0.003±0.001)ng/mL，经过统计学分析发现差异有统计学意义。左心室射血分数(LVEF)与CHF患者cTNT浓度之间存在负相关关系(r=-0.482，P<0.01)。结论 CHF患者中血清cTNT浓度会出现较为明显的升高，升高程度与心衰的严重程度相一致，临床中可以根据CHF患者危险性分层现象开展针对性的治疗措施，在临床治疗中具有指导意义。
目的：研究充血性心力衰竭患者(CHF)病人血清心肌肌鈣蛋白T(cTNT)升高與否，以及探討升高程度與心衰嚴重程度之間的關繫。方法該研究選取該院2012年3月-2014年4月期間在該院接受住院治療的充血性心力衰竭患者65例為研究對象，選擇同期門診體檢的健康患者65例為對照組，通過運用電化學髮光免疫分析法進行測定。結果兩組患者在性彆、年齡、學歷等人口學特徵上均不存在差異，髮現研究組cTNT濃度高達(0.172±0.062)ng/mL，而對照組濃度僅為(0.003±0.001)ng/mL，經過統計學分析髮現差異有統計學意義。左心室射血分數(LVEF)與CHF患者cTNT濃度之間存在負相關關繫(r=-0.482，P<0.01)。結論 CHF患者中血清cTNT濃度會齣現較為明顯的升高，升高程度與心衰的嚴重程度相一緻，臨床中可以根據CHF患者危險性分層現象開展針對性的治療措施，在臨床治療中具有指導意義。
목적：연구충혈성심력쇠갈환자(CHF)병인혈청심기기개단백T(cTNT)승고여부，이급탐토승고정도여심쇠엄중정도지간적관계。방법해연구선취해원2012년3월-2014년4월기간재해원접수주원치료적충혈성심력쇠갈환자65례위연구대상，선택동기문진체검적건강환자65례위대조조，통과운용전화학발광면역분석법진행측정。결과량조환자재성별、년령、학력등인구학특정상균불존재차이，발현연구조cTNT농도고체(0.172±0.062)ng/mL，이대조조농도부위(0.003±0.001)ng/mL，경과통계학분석발현차이유통계학의의。좌심실사혈분수(LVEF)여CHF환자cTNT농도지간존재부상관관계(r=-0.482，P<0.01)。결론 CHF환자중혈청cTNT농도회출현교위명현적승고，승고정도여심쇠적엄중정도상일치，림상중가이근거CHF환자위험성분층현상개전침대성적치료조시，재림상치료중구유지도의의。
Objective To study whether the level of cardiac troponin T (cTNT) increases in patients with congestive heart failure (CHF) and the correlation between it and the severity of CHF. Methods 65 cases with CHF underwent hospitalization in our hospi-tal from March 2012 to April 2014 were selected as the subjects and other 65 healthy people underwent clinic physical examina-tion during the same period were selected as the control group. And electrochemiluminescence immunoassay was used to measure the level of cTNT in all the subjects in the two groups. Results There were no differences in gender, age, education and other de-mographic characteristics between the two groups. The level of cTNT of the study group was as high as 0.172±0.062ng/ml, while that of the control group was only 0.003±0.001ng/ml, the difference between the two groups was statistically significant. The left ventricular ejection fraction (LVEF) was negatively correlated with the cTNT concentration in the CHF patients (r=-0.482, P<0.01). Conclusion The concentration of serum cTNT in CHF patients will appear obvious rise, and its degree of elevation is consistent with the severity of heart failure. Targeted treatment based on the risk stratification phenomenon in CHF patients is of guiding sig-nificance in clinical treatment.
