中外医疗
中外醫療
중외의료
CHINA FOREIGN MEDICAL TREATMENT
2015年
13期
144-145
,共2页
胸腔注射%异烟肼%结核性胸膜炎%胸膜肥厚粘连
胸腔註射%異煙肼%結覈性胸膜炎%胸膜肥厚粘連
흉강주사%이연정%결핵성흉막염%흉막비후점련
Pleural injection%Isoniazid%Tuberculous pleurisy%Pachynsis and adherence of pleura
目的：探讨胸腔注射异烟肼治疗结核性胸膜炎的临床疗效。方法将84例符合入选标准的结核性胸膜炎患者随机分为对照组(n=42)和观察组(n=42)。对照组给予抗结核药物及胸腔穿刺抽液治疗，观察组在对照组的基础上于给予胸腔注射异烟肼治疗。比较两组患者临床疗效，并随访6个月，比较胸膜肥厚粘连发生情况。结果观察组的总有效率为92.8%，明显高于对照组76.2%的总有效率，比较差异有统计学意义(P<0.05)。随访6个月，观察组2例发生胸膜肥厚粘连，发生率为4.8%，对照组9例发生胸膜肥厚粘连，发生率为21.4%。与对照组相比，观察组胸膜肥厚粘连发生率显著降低(P<0.05)。结论常规治疗基础上给予胸腔注射异烟肼治疗结核性胸膜炎疗效可靠，可以显著提高治疗疗效，并降低胸膜肥厚粘连发生率，临床上值得进一步研究。
目的：探討胸腔註射異煙肼治療結覈性胸膜炎的臨床療效。方法將84例符閤入選標準的結覈性胸膜炎患者隨機分為對照組(n=42)和觀察組(n=42)。對照組給予抗結覈藥物及胸腔穿刺抽液治療，觀察組在對照組的基礎上于給予胸腔註射異煙肼治療。比較兩組患者臨床療效，併隨訪6箇月，比較胸膜肥厚粘連髮生情況。結果觀察組的總有效率為92.8%，明顯高于對照組76.2%的總有效率，比較差異有統計學意義(P<0.05)。隨訪6箇月，觀察組2例髮生胸膜肥厚粘連，髮生率為4.8%，對照組9例髮生胸膜肥厚粘連，髮生率為21.4%。與對照組相比，觀察組胸膜肥厚粘連髮生率顯著降低(P<0.05)。結論常規治療基礎上給予胸腔註射異煙肼治療結覈性胸膜炎療效可靠，可以顯著提高治療療效，併降低胸膜肥厚粘連髮生率，臨床上值得進一步研究。
목적：탐토흉강주사이연정치료결핵성흉막염적림상료효。방법장84례부합입선표준적결핵성흉막염환자수궤분위대조조(n=42)화관찰조(n=42)。대조조급여항결핵약물급흉강천자추액치료，관찰조재대조조적기출상우급여흉강주사이연정치료。비교량조환자림상료효，병수방6개월，비교흉막비후점련발생정황。결과관찰조적총유효솔위92.8%，명현고우대조조76.2%적총유효솔，비교차이유통계학의의(P<0.05)。수방6개월，관찰조2례발생흉막비후점련，발생솔위4.8%，대조조9례발생흉막비후점련，발생솔위21.4%。여대조조상비，관찰조흉막비후점련발생솔현저강저(P<0.05)。결론상규치료기출상급여흉강주사이연정치료결핵성흉막염료효가고，가이현저제고치료료효，병강저흉막비후점련발생솔，림상상치득진일보연구。
Objective To investigate the clinical effect of pleural injection by isoniazid in the treatment of tuberculous pleurisy. Methods 84 cases of tuberculous pleurisy meeting the inclusion criteria were randomly divided into two groups equally. The con-trol group was given antituberculous drugs and thoracic drainage. Besides that, the observation group was given pleural injection by isoniazid. Then, the curative efficacy and incidence of pachynsis and adherence of pleura after the six-month follow-up were compared between the two groups. Results The observation group had a therapeutic efficiency ratio of 92.8%, which was signifi-cantly higher than that of 76.2%in the control group (P<0.05). In the six-month follow-up, there's two cases of pachynsis and ad-herence of pleura in the observation group with the incidence of 4.8%, while there's nine cases of pachynsis and adherence of pleura in the control group with the incidence of 21.4%. In comparison with the control group, the incidence of pachynsis and ad-herence of pleura in the observation group was statistically lower (P<0.05). Conclusion Treatment of pleural injection by isoniazid in patients with tuberculous pleurisy is effective, which can significantly increase curative efficacy and reduce incidence of pachynsis and adherence of pleura.
