中国社区医师
中國社區醫師
중국사구의사
Chinese Community Doctors
2015年
19期
95-96
,共2页
纤维蛋白原%冠状动脉病变%危险因素
纖維蛋白原%冠狀動脈病變%危險因素
섬유단백원%관상동맥병변%위험인소
Fibrinogen%Coronary artery disease%Risk factors
目的：探讨冠心病患者血浆纤维蛋白原水平的变化与冠状动脉病变及其危险因素的关系。方法：对拟诊冠心病患者检测血浆纤维蛋白原水平并行冠状动脉造影术。结果：冠心病患者血浆纤维蛋白原水平与冠脉造影正常者相比差异有统计学意义(P＜0.01)，且与冠脉病变范围和狭窄程度呈正比(P＜0.05)，与年龄、高脂血症和多个危险因素密切相关，组间比较差异有统计学意义(P＜0.01)。结论：血浆纤维蛋白原水平增高是冠心病一个主要危险因素，且其他危险因素越多，血浆纤维蛋白原水平越高，风险越大。有效降低血浆纤维蛋白原水平可作为预防和治疗冠心病的一个指标。
目的：探討冠心病患者血漿纖維蛋白原水平的變化與冠狀動脈病變及其危險因素的關繫。方法：對擬診冠心病患者檢測血漿纖維蛋白原水平併行冠狀動脈造影術。結果：冠心病患者血漿纖維蛋白原水平與冠脈造影正常者相比差異有統計學意義(P＜0.01)，且與冠脈病變範圍和狹窄程度呈正比(P＜0.05)，與年齡、高脂血癥和多箇危險因素密切相關，組間比較差異有統計學意義(P＜0.01)。結論：血漿纖維蛋白原水平增高是冠心病一箇主要危險因素，且其他危險因素越多，血漿纖維蛋白原水平越高，風險越大。有效降低血漿纖維蛋白原水平可作為預防和治療冠心病的一箇指標。
목적：탐토관심병환자혈장섬유단백원수평적변화여관상동맥병변급기위험인소적관계。방법：대의진관심병환자검측혈장섬유단백원수평병행관상동맥조영술。결과：관심병환자혈장섬유단백원수평여관맥조영정상자상비차이유통계학의의(P＜0.01)，차여관맥병변범위화협착정도정정비(P＜0.05)，여년령、고지혈증화다개위험인소밀절상관，조간비교차이유통계학의의(P＜0.01)。결론：혈장섬유단백원수평증고시관심병일개주요위험인소，차기타위험인소월다，혈장섬유단백원수평월고，풍험월대。유효강저혈장섬유단백원수평가작위예방화치료관심병적일개지표。
Objective:To explore the relationship between plasma fibrinogen changes and the coronary lesion and risk factors. Methods:500 patients with suspected coronary artery disease were selected.They were given the plasma fibrinogen determination and coronary artery angiography.Results:In patients with coronary heart disease,compared with cases with normal coronary angiography,there was significant difference in the level of plasma fibrinogen(P<0.01).It was proportional to the area of coronary artery lesions and the degree of stenosis(P<0.05).It was closely related with age,hyperlipidemia and multiple risk factors,and the difference between groups was statistically significant(P<0.01).Conclusion:The increased plasma fibrinogen level was one of the main risk factors of coronary artery disease,and other risk factors were more,plasma fibrinogen level was higher,the risk was greater.Effectively reducing the plasma fibrinogen levels can be used as an index for the prevention and treatment of coronary heart disease.
