中国社区医师
中國社區醫師
중국사구의사
Chinese Community Doctors
2015年
19期
87-88
,共2页
川芎嗪%胸部肿瘤%肺损伤
川芎嗪%胸部腫瘤%肺損傷
천궁진%흉부종류%폐손상
Ligustrazine%Thoracic tumor%Lung injury
目的：分析川芎嗪对胸部肿瘤放射治疗后肺损伤的干预作用。方法：收治胸部肿瘤放射治疗患者80例，随机分为对照组和观察组。对照组给予常规胸部肿瘤放射治疗，观察组在对照组的基础上服用川芎嗪，测定放射治疗前后的血浆 TGF-β1。结果：放射治疗后，观察组血浆 TGF-β1(5.81±2.89)ng/mL明显低于对照组的(11.7±5.49)ng/mL(P＜0.05)。结论：川芎嗪能够抑制放射治疗后血浆 TGF-β1的过度表达，能够有效地抑制和干预患者的肺损伤，提高患者的生活质量，减轻不良反应。
目的：分析川芎嗪對胸部腫瘤放射治療後肺損傷的榦預作用。方法：收治胸部腫瘤放射治療患者80例，隨機分為對照組和觀察組。對照組給予常規胸部腫瘤放射治療，觀察組在對照組的基礎上服用川芎嗪，測定放射治療前後的血漿 TGF-β1。結果：放射治療後，觀察組血漿 TGF-β1(5.81±2.89)ng/mL明顯低于對照組的(11.7±5.49)ng/mL(P＜0.05)。結論：川芎嗪能夠抑製放射治療後血漿 TGF-β1的過度錶達，能夠有效地抑製和榦預患者的肺損傷，提高患者的生活質量，減輕不良反應。
목적：분석천궁진대흉부종류방사치료후폐손상적간예작용。방법：수치흉부종류방사치료환자80례，수궤분위대조조화관찰조。대조조급여상규흉부종류방사치료，관찰조재대조조적기출상복용천궁진，측정방사치료전후적혈장 TGF-β1。결과：방사치료후，관찰조혈장 TGF-β1(5.81±2.89)ng/mL명현저우대조조적(11.7±5.49)ng/mL(P＜0.05)。결론：천궁진능구억제방사치료후혈장 TGF-β1적과도표체，능구유효지억제화간예환자적폐손상，제고환자적생활질량，감경불량반응。
Objective:To analyze the intervention effect of ligustrazine on the lung injury after thoracic tumor radiotherapy. Methods:80 patients with thoracic tumor radiotherapy were selected.They were randomly divided into the observation group and the control group.The control group was given routine thoracic tumor radiotherapy.The observation group was given ligustrazine on the basis of the control group.The plasma TGF-beta 1 was measured before and after radiotherapy.Results:After radiotherapy,the plasma TGF-beta 1 (5.81±2.89)ng/mL of the observation group was significantly lower than (11.7±5.49)ng/mL of the control group(P<0.05).Conclusion:Using ligustrazine can inhibit the over expression of plasma TGF-beta 1 after radiotherapy.It can effectively inhibit and intervene the lung injury of patients,improve the life quality of patients,and reduce the adverse reaction.
