CAJ | 학술논문

目的：分析不同血钾水平的库欣综合症患者的临床特点及并发症发生趋势。方法筛选2013年12月-2015年1月该院收治的库欣综合症患者156例，作为研究对象。根据患者血钾水平将其分为正常组与低血钾组，正常组62例，低血钾组94例，比较两组患者的临床特点，分析两组患者并发症发生特点。结果与正常组比较低血钾组患者男性构成比高于女性，同时低血钾组男性患者病程、血压、血脂与正常组比较，差异有统计学意义(P<0.05)；低血钾组紫纹、瘀斑、碱中毒和下肢水肿发生率明显高于正常组；低血钾组并发症发生率明显高于正常组，并且以心律失常最为常见。结论库欣综合症合并低血钾者常见于男性患者，患者表现为病程短、代谢异常加重、体征突出等，库欣综合症发生心脑血管并发症发生率较高，而低血钾患者发生率更高。
목적：분석불동혈갑수평적고흔종합증환자적림상특점급병발증발생추세。방법사선2013년12월-2015년1월해원수치적고흔종합증환자156례，작위연구대상。근거환자혈갑수평장기분위정상조여저혈갑조，정상조62례，저혈갑조94례，비교량조환자적림상특점，분석량조환자병발증발생특점。결과여정상조비교저혈갑조환자남성구성비고우녀성，동시저혈갑조남성환자병정、혈압、혈지여정상조비교，차이유통계학의의(P<0.05)；저혈갑조자문、어반、감중독화하지수종발생솔명현고우정상조；저혈갑조병발증발생솔명현고우정상조，병차이심률실상최위상견。결론고흔종합증합병저혈갑자상견우남성환자，환자표현위병정단、대사이상가중、체정돌출등，고흔종합증발생심뇌혈관병발증발생솔교고，이저혈갑환자발생솔경고。
Objective To analyze the clinical characteristics of Cushing's syndrome in patients with different serumal potassium levels and its complications. Methods 156 patients with Cushing's syndrome admitted to our hospital from December 2013 to Jan-uary 2015 were selected as the research object and divided into normal group (n=62) and hypokalemia group (n=94) according to potassium levels. The clinical characteristics and complications of the two groups were analyzed. Results Constituent ratio of male patients in the hypokalemia group was higher than that in the normal group, and there were statistically significant differences be-tween the duration of disease, blood pressure, blood lipid of the male patients in the hypokalemia group and those in the normal group (P<0.05). The incidences of purple striae, ecchymosis, alkalosis, lower extremity edema, and the complications (arrhythmias and so on) rate of the hypokalemia group were obviously higher than those of the normal group. Conclusion Hypokalemia is more common in male patients with Cushing's syndrome, with the clinical characteristics of short duration, exacerbation of abnormal metabolism and prominent body sign. Patients with Cushing's syndrome have higher incidence of cardiovascular complications, es-pecially for those with additional hypokalemia.