CAJ | 학술논문

目的：探讨颅内血管狭窄与短暂性脑缺血发作1周内转化为脑梗死的影响因素。方法对该院收住的113例短暂性脑缺血发作患者进行临床资料回顾性分析。根据患者有无在发作1内周发生脑梗死分为发作组与非发作组，采用Pearson单因素分析各临床相关因素与短暂性脑缺血发作1周内转化为脑梗死的关系，对于单因素分析存在统计学意义的因素，进行多因素Logistic回归分析。结果Pearson单因素分析显示，年龄、颅内血管狭窄、高血压病史、糖尿病史、冠心病史、脑血管病史等均是影响短暂性脑缺血发作1周内转化为脑梗死的危险因素（P<0.05）。对上述因素进行多因素Logistic回归分析，提示颅内血管狭窄、高血压病史、糖尿病史、冠心病史、脑血管病史等属于影响短暂性脑缺血发作1周内转化为脑梗死的独立危险因素（P<0.05）。结论颅内血管狭窄、高血压病史、糖尿病史、冠心病史、脑血管病史等属于影响短暂性脑缺血发作1周内转化为脑梗死的危险因素。对于存在上述病史的患者，应早期给予药物干预，避免短暂性脑缺血的发生。
목적：탐토로내혈관협착여단잠성뇌결혈발작1주내전화위뇌경사적영향인소。방법대해원수주적113례단잠성뇌결혈발작환자진행림상자료회고성분석。근거환자유무재발작1내주발생뇌경사분위발작조여비발작조，채용Pearson단인소분석각림상상관인소여단잠성뇌결혈발작1주내전화위뇌경사적관계，대우단인소분석존재통계학의의적인소，진행다인소Logistic회귀분석。결과Pearson단인소분석현시，년령、로내혈관협착、고혈압병사、당뇨병사、관심병사、뇌혈관병사등균시영향단잠성뇌결혈발작1주내전화위뇌경사적위험인소（P<0.05）。대상술인소진행다인소Logistic회귀분석，제시로내혈관협착、고혈압병사、당뇨병사、관심병사、뇌혈관병사등속우영향단잠성뇌결혈발작1주내전화위뇌경사적독립위험인소（P<0.05）。결론로내혈관협착、고혈압병사、당뇨병사、관심병사、뇌혈관병사등속우영향단잠성뇌결혈발작1주내전화위뇌경사적위험인소。대우존재상술병사적환자，응조기급여약물간예，피면단잠성뇌결혈적발생。
Objective To discuss influencing factors of intracranial vascular stenosis and transient ischemic attack were converted to cerebral infarction within one week. Methods Retrospective analysis on the clinical data of the 113 patients admitted in our hospital with transient ischemic attack was made. According to the cases whether they had cerebral infraction within one week, these patients were divided into attack group and non-attack group. Using Pearson univariate to analyze the clinical relevant factors and the relationship between them respectively, and for statistically significant factors in single factor analysis, multivariate logistic regression analysis was used. Results Results Pearson univariate analysis showed that age, intracranial vascular stenosis, history of hypertension, history of diabetes, history of coronary heart disease, cerebrovascular disease, etc. are effects of the risk factors of transient ischemic attack was converted to cerebral infarction within one week (P<0.05). Multivariate logistic regression analysis were made to the above mentioned factors, and suggestive hints were that intracranial vascular stenosis, hypertension history, diabetes history, history of coronary heart disease, cerebrovascular disease, etc. belonging to independent risk factors of transient ischemic attack converted to cerebral infarction within one week (P<0.05). Conclusion Intracranial vascular stenosis, hypertension history, diabetes history, history of coronary heart disease, cerebrovascular disease, etc. were risk factors of transient ischemic attack converted to cerebral infarction within one week. For patients with the history of the above mentioned disease, early intervention should be given to avoid the occurrence of transient cerebral ischemia.