中国社区医师
中國社區醫師
중국사구의사
Chinese Community Doctors
2015年
23期
35-35,37
,共2页
糖尿病肾病%前列地尔%肾损害%蛋白尿
糖尿病腎病%前列地爾%腎損害%蛋白尿
당뇨병신병%전렬지이%신손해%단백뇨
Diabetic nephropathy%Alprostadil%Renal damage%Proteinuria
目的：探讨前列地尔治疗对糖尿病肾病的治疗效果。方法：收治糖尿病肾脏病患者84例，将其分为前列地尔治疗组(A组)43例，对照组(B组)41例，两组均给予糖尿病饮食、控制血糖、稳定血压、降血脂、抗凝、改善微循环等对症基础治疗。结果：A组：24 h尿蛋白定量增加31例，稳定9例，减少3例；eGFR稳定8例，下降35例，其中发生肾衰竭2例。B 组：24 h 尿蛋白定量增加38例，稳定3例；eGFR 稳定4例，下降37例，其中5例发生肾衰竭。结论：前列地尔的规范化使用可有效缓解糖尿病肾病的发展。
目的：探討前列地爾治療對糖尿病腎病的治療效果。方法：收治糖尿病腎髒病患者84例，將其分為前列地爾治療組(A組)43例，對照組(B組)41例，兩組均給予糖尿病飲食、控製血糖、穩定血壓、降血脂、抗凝、改善微循環等對癥基礎治療。結果：A組：24 h尿蛋白定量增加31例，穩定9例，減少3例；eGFR穩定8例，下降35例，其中髮生腎衰竭2例。B 組：24 h 尿蛋白定量增加38例，穩定3例；eGFR 穩定4例，下降37例，其中5例髮生腎衰竭。結論：前列地爾的規範化使用可有效緩解糖尿病腎病的髮展。
목적：탐토전렬지이치료대당뇨병신병적치료효과。방법：수치당뇨병신장병환자84례，장기분위전렬지이치료조(A조)43례，대조조(B조)41례，량조균급여당뇨병음식、공제혈당、은정혈압、강혈지、항응、개선미순배등대증기출치료。결과：A조：24 h뇨단백정량증가31례，은정9례，감소3례；eGFR은정8례，하강35례，기중발생신쇠갈2례。B 조：24 h 뇨단백정량증가38례，은정3례；eGFR 은정4례，하강37례，기중5례발생신쇠갈。결론：전렬지이적규범화사용가유효완해당뇨병신병적발전。
Objective:To investigate the effect of alprostadil in the treatment of diabetic nephropathy.Methods:84 patients with diabetic kidney disease were selected.They were divided into the alprostadil treatment group(group A) with 43 cases,and the control group(group B) with 41 cases.All of the patients in the two groups were given symptomatic treatment,including diabetic diet,controlling blood glucose,stable blood pressure,hypolipidemic,anticoagulant,improve microcirculation etc.Results:Group A:There 31 cases were increased in urinary protein quantitative during 24 h,and 9 cases were stable,3 cases were decreased;and 8 cases with stable EGFR,35 cases were reduced,in which there were 2 cases had renal failure.Group B:There 38 cases were increased in urinary protein quantitative during 24 h,and 5 cases were stable;and 4 cases with stable EGFR,37 cases were reduced,in which there were 5 cases had renal failure.Conclusion:Standardized use of alprostadil can alleviate the development of diabetic kidney disease effectively.
