CAJ | 학술논문

目的：探讨腹腔镜和开放手术对老年胆囊结石患者应激反应的影响。方法：收治胆囊结石老年患者72例，分为开腹组和腹腔镜组，比较两组患者的血清CRP浓度、皮质醇浓度、IL-6和IL-10浓度。结果：腹腔镜组的血清IL-6浓度低于开腹组，IL-10明显高于开腹组，CRP 浓度和术后第1天的皮质醇浓度明显低于开腹组(P＜0.05)。结论：腹腔镜手术治疗老年胆囊结石患者具有创伤小、痛苦小、恢复快等优点，患者的术后应激反应比开放手术轻，可以作为老年胆囊结石的首选手术方式。
목적：탐토복강경화개방수술대노년담낭결석환자응격반응적영향。방법：수치담낭결석노년환자72례，분위개복조화복강경조，비교량조환자적혈청CRP농도、피질순농도、IL-6화IL-10농도。결과：복강경조적혈청IL-6농도저우개복조，IL-10명현고우개복조，CRP 농도화술후제1천적피질순농도명현저우개복조(P＜0.05)。결론：복강경수술치료노년담낭결석환자구유창상소、통고소、회복쾌등우점，환자적술후응격반응비개방수술경，가이작위노년담낭결석적수선수술방식。
Objective:To explore the stress reaction of laparoscopic and open operation in the treatment of elderly patients with cholecystolithiasis.Methods:72 cases of elderly patients with cholecystolithiasis were selected.They were divided into the laparoscope group and open operation group.We compared serum CRP concentration,cortisol,IL-6 and IL-10 concentration of the two groups.Results:In the laparoscope group,serum IL-6 concentration was lower than the open operation group;IL-10 was significantly higher than that in the open operation group;the concentration of CRP and cortisol concentration at the first day after operation were obviously lower than the open operation group(P<0.05).Conclusion:Laparoscopic surgery in the treatment of elderly patients with cholecystolithiasis had many advantages,such as small trauma,less pain,faster recovery and so on.Compared with open surgery,the postoperative stress reaction of patients was light,and it can be used as the first choice for elderly patients with cholecystolithiasis.