CAJ | 학술논문

目的：评价多排螺旋CT灌注成像（ MSCTP ）在甲状腺癌诊断及鉴别诊断中的应用价值。方法选取甲状腺良性病变患者18例作为良性组，甲状腺癌患者22例作为恶性组。2组患者均进行MSCTP检查，测量并分析比较2组中病变组织与正常组织的血流量（BF）、血容量（BV）、表面通透性（PS）及峰值时间（TTP）灌注参数值。结果良性组病变组织与正常组织的BF、BV、PS和TTP的M值差值较小，病变组织／正常组织的比值较小，差异无统计学意义（ P＞00．5）。恶性组病变组织与正常组织的BF、BV和PS的M值差值较大，病变组织BF、BV和PS的M值明显低于正常组织，病变组织／正常组织的比值较大，差异有统计学意义（ P＜0．001）；而TTP的M值差值较小，病变组织／正常组织的比值较小，差异无统计学意义（P＞0．05）。结论甲状腺癌的病变组织与正常组织的MSCT检查指标中PBF、BV和PS的M值差值及病变组织／正常组织的比值在甲状腺癌的诊断及鉴别诊断中具有重要的应用价值。
목적：평개다배라선CT관주성상（ MSCTP ）재갑상선암진단급감별진단중적응용개치。방법선취갑상선량성병변환자18례작위량성조，갑상선암환자22례작위악성조。2조환자균진행MSCTP검사，측량병분석비교2조중병변조직여정상조직적혈류량（BF）、혈용량（BV）、표면통투성（PS）급봉치시간（TTP）관주삼수치。결과량성조병변조직여정상조직적BF、BV、PS화TTP적M치차치교소，병변조직／정상조직적비치교소，차이무통계학의의（ P＞00．5）。악성조병변조직여정상조직적BF、BV화PS적M치차치교대，병변조직BF、BV화PS적M치명현저우정상조직，병변조직／정상조직적비치교대，차이유통계학의의（ P＜0．001）；이TTP적M치차치교소，병변조직／정상조직적비치교소，차이무통계학의의（P＞0．05）。결론갑상선암적병변조직여정상조직적MSCT검사지표중PBF、BV화PS적M치차치급병변조직／정상조직적비치재갑상선암적진단급감별진단중구유중요적응용개치。
Objective It is to evaluate the values of using MSCT perfusion imaging in the diagnosis and differential diagno -sis of thyroid carcinoma .Methods 40 cases of thyroid neoplasm were divided into two groups:18 cases of benign tumors as benign group , and 22 cases of malignant thyroid tumors as malignant group .The patients in both groups were scanned with MSCT perfusion, their blood flow (BF), blood volume(BV), permeability surface (PS)and peak time were measured, com-pared and statistically analyzed .Results The mean values of the parameters of BF , BV, PS and TTP in lesion tissues and nor-mal tissues of the group with benign tumors were smaller , the ratio of lesion tissues/normal tissues was small , and the differ-ences were not significant (P>0.05).The mean values of the parameters of BF , BV, PS in lesion tissues and normal tissues of malignant group were bigger .M value of BF, BV and PS in lesion tissue were obviously lower than that in normal tissue , the ratio of lesion tissues/normal tissues were bigger, the differences were significant(P<0.001), but M value of TTP was smal-ler, the ratio of lesion tissues/normal tissues was smaller, and the difference was not significant (P>0.05).Conclusion With CT perfusion imaging , the difference and ratio of BF ,BV and PS between the lesion tissues and the normal tissues play an important clinical role in the diagnosis and differential diagnosis of thyroid carcinoma .