中外医疗
中外醫療
중외의료
CHINA FOREIGN MEDICAL TREATMENT
2015年
23期
184-185,196
,共3页
ABO血型%RhD血型%新生儿溶血三项试验
ABO血型%RhD血型%新生兒溶血三項試驗
ABO혈형%RhD혈형%신생인용혈삼항시험
ABO blood type%RhD blood group%HDN three trials testing of newborn
目的：探讨新生儿溶血三项试验检测数据,为该地区新生儿溶血病(hemolytic disease of the new born,HDN)的诊治提供依据。方法采用微柱凝胶法对整群选取的该院879例新生儿高胆红素血症的患儿进行AB0、RhD血型鉴定及新生儿溶血三项(直接抗人球蛋白试验、血清游离抗体试验、抗体释放试验)检测,各组间率的比较使用SPSS17.0软件包,各血型HDN检出率HDN阳性分布的比较采用χ2检验,P<0.05为差异有统计学意义。结果送检样本中,A、B、0、AB血型阳性率为23.34%、20.46%、0.00%和3.77%,；Rh-HDN阳性率依次为0.70%、1.16%、4.64%和1.89%,组中各血型阳性率分布差异有统计学意义(P<0.05)；所有AB0-HDN阳性样本中,A、B、0、AB血型比例分别为54.92%、43.44%、0.00%和1.64%, Rh-HDN中各血型阳性率分别为10.53%、15.79%、68.42%和5.26%,HDN确诊患儿中血型分布差异有统计学意义(P<0.05)；结论HDN主要以AB0血型不合引起,Rh-HDN少见；ABO-HDN中以A、B型血新生儿为主,Rh-HDN中则多见于O型血新生儿。
目的：探討新生兒溶血三項試驗檢測數據,為該地區新生兒溶血病(hemolytic disease of the new born,HDN)的診治提供依據。方法採用微柱凝膠法對整群選取的該院879例新生兒高膽紅素血癥的患兒進行AB0、RhD血型鑒定及新生兒溶血三項(直接抗人毬蛋白試驗、血清遊離抗體試驗、抗體釋放試驗)檢測,各組間率的比較使用SPSS17.0軟件包,各血型HDN檢齣率HDN暘性分佈的比較採用χ2檢驗,P<0.05為差異有統計學意義。結果送檢樣本中,A、B、0、AB血型暘性率為23.34%、20.46%、0.00%和3.77%,；Rh-HDN暘性率依次為0.70%、1.16%、4.64%和1.89%,組中各血型暘性率分佈差異有統計學意義(P<0.05)；所有AB0-HDN暘性樣本中,A、B、0、AB血型比例分彆為54.92%、43.44%、0.00%和1.64%, Rh-HDN中各血型暘性率分彆為10.53%、15.79%、68.42%和5.26%,HDN確診患兒中血型分佈差異有統計學意義(P<0.05)；結論HDN主要以AB0血型不閤引起,Rh-HDN少見；ABO-HDN中以A、B型血新生兒為主,Rh-HDN中則多見于O型血新生兒。
목적：탐토신생인용혈삼항시험검측수거,위해지구신생인용혈병(hemolytic disease of the new born,HDN)적진치제공의거。방법채용미주응효법대정군선취적해원879례신생인고담홍소혈증적환인진행AB0、RhD혈형감정급신생인용혈삼항(직접항인구단백시험、혈청유리항체시험、항체석방시험)검측,각조간솔적비교사용SPSS17.0연건포,각혈형HDN검출솔HDN양성분포적비교채용χ2검험,P<0.05위차이유통계학의의。결과송검양본중,A、B、0、AB혈형양성솔위23.34%、20.46%、0.00%화3.77%,；Rh-HDN양성솔의차위0.70%、1.16%、4.64%화1.89%,조중각혈형양성솔분포차이유통계학의의(P<0.05)；소유AB0-HDN양성양본중,A、B、0、AB혈형비례분별위54.92%、43.44%、0.00%화1.64%, Rh-HDN중각혈형양성솔분별위10.53%、15.79%、68.42%화5.26%,HDN학진환인중혈형분포차이유통계학의의(P<0.05)；결론HDN주요이AB0혈형불합인기,Rh-HDN소견；ABO-HDN중이A、B형혈신생인위주,Rh-HDN중칙다견우O형혈신생인。
Objective To investigate the values of the three tests of hemolytic disease of the newborn (HDN) so as to provide reference for the diagnosis and treatment of the disease in the local district. Methods Using the micro column gel method to test ABO, RhD blood grouping and hemolytic three(direct Coombs test , serum free antibody test, antibody release test) of 879 children with neonatal hyperbilirubinemia in the hospital.Compared rates between groups using SPSS17.0 package, and compared the relevance ratio of HDN and HDN positive distribution of each blood type using χ2 test, and P<0.05 was considered statistically significant. Results Within the submission samples, positive rate of A, B, O, AB blood type was 23.34%, 20.46%, 0.00% and 3.77%respectively. Rh-HDN-positive rate was 0.70%, 1.16%, 4.64%and 1.89%respectively. The distribution of positive rate of each blood type group had statistically significant differences (P<0.05);All ABO -HDN positive samples, A, B, O, AB blood type ratio was 54.92%, 43.44%, 0.00%and 1.64% respectively, and in each blood type Rh-HDN positive rates was 10.53%, 15.79%, 68.42% and 5.26% respectively,and blood type distribution of children diagnosed as HDN had statistically significant differences (P<0.05). Conclusion HDN caused mainly by ABO blood type incompatibility, Rh-HDN rare; and ABO-HDN was mainly occurred in newborns with A or B-type blood, while Rh-HDN is more common in newborns with O blood type.
