CAJ | 학술논문

目的：分析替米沙坦联合钙离子拮抗剂治疗糖尿病肾病并发高血压病的临床疗效。方法随机选取该院2013年5月—2015年1月收治的120例2型糖尿病肾病合并高血压患者，随机分为对照组和观察组各60例，对照组的患者口服替米沙坦片；观察组患者则加用钙离子拮抗剂拉西地平片，两组均连续治疗2个月。监测治疗前后血压、肾功能水平变化，计算有效率。结果对照组患者的有效率达到71.6%，明显低于观察组患者的有效率90%(P<0.05)；观察组患者的血压、肾功能改善情况优于对照组患者(P<0.05)。结论替米沙坦联合钙离子拮抗剂药物治疗糖尿病肾病并发高血压疗效确切，利于改善患者的血压及肾功能，值得临床应用并推广。
목적：분석체미사탄연합개리자길항제치료당뇨병신병병발고혈압병적림상료효。방법수궤선취해원2013년5월—2015년1월수치적120례2형당뇨병신병합병고혈압환자，수궤분위대조조화관찰조각60례，대조조적환자구복체미사탄편；관찰조환자칙가용개리자길항제랍서지평편，량조균련속치료2개월。감측치료전후혈압、신공능수평변화，계산유효솔。결과대조조환자적유효솔체도71.6%，명현저우관찰조환자적유효솔90%(P<0.05)；관찰조환자적혈압、신공능개선정황우우대조조환자(P<0.05)。결론체미사탄연합개리자길항제약물치료당뇨병신병병발고혈압료효학절，리우개선환자적혈압급신공능，치득림상응용병추엄。
Objective To investigate the clinical curative effect for treating diabetic kidney disease complicated with hypertension patients with telmisartan combined calcium antagonists. Methods 120 diabetic kidney disease complicated with hypertension pa-tients were randomly divided into a control group of 60cases and an observation group of 60 cases from May 2013 to January 2015. Patients in the control group were treated with telmisartan tablets;while patients in the observation group were treated with calcium antagonists on the basis of control treatment, 2 months for treatment. The paper was focus on monitoring the blood pressure and kidney function before and after treatment, and calculating the effective clinical treatment. Results The efficiency for patients in the control group was 71.6%, which was lower than that of the observation group 90%(P<0.05);The improvement of blood pressure and kidney function of the patients in the observation group were better than that in the control group, and the level of DBP, SBP, Scr, 24 Upro and UAER were lower than that in the control group (P<0.05); Conclusion The therapy has curative effect,which is good to improve the blood pressure and kidney function, is worth of wide application in the clinical practice.