CAJ | 학술논문

目的：探讨坎地沙坦酯、依那普利与胺碘酮联合应用在高血压合并阵发性房颤中的效果。方法整群选取2012年5月—2014年2月该院收治的83例高血压合并阵发性房颤病人,按照随机数字表法分为A组(n=41)和B组(n=42)。A组给予坎地沙坦酯、胺碘酮联合治疗,B组给予依那普利、胺碘酮联合治疗,对比两组治疗效果。结果A组、B组治疗后6个月、12个月的SBP水平、DBP水平、房颤发作次数均显著地低于治疗前(P<0.05)；A组、B组治疗后6个月、治疗后12个月左心房内径与治疗前相比,差异无统计学意义(P>0.05)；A组、B组组间治疗前、治疗后6个月、治疗后12个月的SBP水平、DBP水平、左心房内径大小、房颤发作次数相比,差异无统计学意义(P>0.05)。结论坎地沙坦酯或者依那普利联合胺碘酮均可有效地治疗高血压合并阵发性房颤,效果确切。
목적：탐토감지사탄지、의나보리여알전동연합응용재고혈압합병진발성방전중적효과。방법정군선취2012년5월—2014년2월해원수치적83례고혈압합병진발성방전병인,안조수궤수자표법분위A조(n=41)화B조(n=42)。A조급여감지사탄지、알전동연합치료,B조급여의나보리、알전동연합치료,대비량조치료효과。결과A조、B조치료후6개월、12개월적SBP수평、DBP수평、방전발작차수균현저지저우치료전(P<0.05)；A조、B조치료후6개월、치료후12개월좌심방내경여치료전상비,차이무통계학의의(P>0.05)；A조、B조조간치료전、치료후6개월、치료후12개월적SBP수평、DBP수평、좌심방내경대소、방전발작차수상비,차이무통계학의의(P>0.05)。결론감지사탄지혹자의나보리연합알전동균가유효지치료고혈압합병진발성방전,효과학절。
Objective To investigate effect of candesartan cilexetil, enalapril combined with amiodarone therapy hypertensive pa-tients with paroxysmal atrial fibrillation. Methods 83 patients were randomly divided into two groups. Group A was given can-desartan cilexetilamiodarone, while Group B was given enalapril and amiodarone. Results SBP,DBP and atrial fibrillation of 6 months and 12 months in two groups was lower than pre-treatment(P<0.05). Comparing pre-treatment,atrial fibrillation of 6 months and 12 months in two groups had no difference (P>0.05). SBP,DBP,atrial fibrillation and left atrium of pre-treatment,6 months and 12 months in two groups had no significant difference (P>0.05). Conclusion Candesartan cilexetil, enalapril combined with amio-darone has a good effect.