中外医疗
中外醫療
중외의료
CHINA FOREIGN MEDICAL TREATMENT
2015年
23期
96-97
,共2页
颅脑外伤%糖皮质激素%脑水肿%血糖水平
顱腦外傷%糖皮質激素%腦水腫%血糖水平
로뇌외상%당피질격소%뇌수종%혈당수평
Craniocerebral trauma%Glucocorticoids%Brain edema%Blood glucose levels
目的：探究在颅脑外伤的临床治疗中糖皮质激素的应用效果。方法整群选取2012年4月—2014年12月在该院治疗的颅脑外伤患者86例，按照随机分组原则将其分为对照组和糖皮质激素治疗组分别为43例，对照组患者采取常规的对症缓解治疗，治疗组患者则在对症治疗的基础上采用糖皮质激素进行治疗，比较两组患者治疗7d后脑组织动态变化、患者血糖以及消化道的出血状况。结果两组患者在治疗7 d后均未出现消化道出血症状，而治疗组患者的脑水肿消退率95.3%和好转情况明显高于对照组69.8%，同时治疗组患者的血糖增高率34.9%情况明显高于对照组18.6%，其差异具有统计学意义(P<0.05)。结论在颅脑外伤的临床治疗中应用糖皮质激素能够显著改善患者的脑水肿状况，但患者的血糖水平有一定的上升，因此在患者的临床应用治疗中糖皮质激素要酌情使用。
目的：探究在顱腦外傷的臨床治療中糖皮質激素的應用效果。方法整群選取2012年4月—2014年12月在該院治療的顱腦外傷患者86例，按照隨機分組原則將其分為對照組和糖皮質激素治療組分彆為43例，對照組患者採取常規的對癥緩解治療，治療組患者則在對癥治療的基礎上採用糖皮質激素進行治療，比較兩組患者治療7d後腦組織動態變化、患者血糖以及消化道的齣血狀況。結果兩組患者在治療7 d後均未齣現消化道齣血癥狀，而治療組患者的腦水腫消退率95.3%和好轉情況明顯高于對照組69.8%，同時治療組患者的血糖增高率34.9%情況明顯高于對照組18.6%，其差異具有統計學意義(P<0.05)。結論在顱腦外傷的臨床治療中應用糖皮質激素能夠顯著改善患者的腦水腫狀況，但患者的血糖水平有一定的上升，因此在患者的臨床應用治療中糖皮質激素要酌情使用。
목적：탐구재로뇌외상적림상치료중당피질격소적응용효과。방법정군선취2012년4월—2014년12월재해원치료적로뇌외상환자86례，안조수궤분조원칙장기분위대조조화당피질격소치료조분별위43례，대조조환자채취상규적대증완해치료，치료조환자칙재대증치료적기출상채용당피질격소진행치료，비교량조환자치료7d후뇌조직동태변화、환자혈당이급소화도적출혈상황。결과량조환자재치료7 d후균미출현소화도출혈증상，이치료조환자적뇌수종소퇴솔95.3%화호전정황명현고우대조조69.8%，동시치료조환자적혈당증고솔34.9%정황명현고우대조조18.6%，기차이구유통계학의의(P<0.05)。결론재로뇌외상적림상치료중응용당피질격소능구현저개선환자적뇌수종상황，단환자적혈당수평유일정적상승，인차재환자적림상응용치료중당피질격소요작정사용。
Objective To explore the clinical application effect of glucocorticoid in the treatment of craniocerebral trauma. Meth-ods 86 cases with craniocerebral trauma were selected which were treated in our hospital during April 2012 to December 2014, and randomly assigned for control group and glucocorticoid treatment group, 43 cases in each group. The control group was treated by conventional symptomatic relief, the treatment group was treated by glucocorticoid on the basis of symptomatic treatment, Dy-namic changes of brain tissue, blood glucose and the bleeding of digestive tract were compared after 7 days. Results 7 days after treatment, both groups not had the symptoms of gastrointestinal bleeding. In treatment group, the regression rate of encephaledema (95.3%) and the improvement rate were significantly higher than the control group (69.8%). The increase rate of blood glucose was 34.9%and was significantly higher than the control group of 18.6%, the difference was statistical significance (P ? 0.05). Conclu-sion In the clinical treatment of craniocerebral trauma, glucocorticoid can significantly improve the patientˊs brain edema condi-tion, but the blood glucose level of patients had a certain rise. Therefore, glucocorticoid should be appropriate to use in the clinical application of treatment.
