中外医疗
中外醫療
중외의료
CHINA FOREIGN MEDICAL TREATMENT
2015年
23期
26-27,29
,共3页
甲状腺癌%女性患者%病理%临床预后
甲狀腺癌%女性患者%病理%臨床預後
갑상선암%녀성환자%병리%림상예후
Thyroid cancer%Female patients%Pathology%Clinical prognosis
目的：探讨女性甲状腺癌的病理特点以及预后影响因素。方法整群选取2008年1月—2012年1月,该院收治的女性甲状腺癌患者148例,回顾分析其临床病理特点以及预后影响因素。结果病理检查显示133例(89.9%)甲状腺乳头状癌(PTC),6例(4.1%)为滤泡状癌(FTC),3例(2.0%)为髓样癌(MTC),6例(4.1%)为未分化癌(ATC)；病理分期Ⅰ~Ⅱ期占45.3%,Ⅲ~Ⅳ期占54.7%；27例(18.24%)为周围组织侵犯,9例(6.1%)为远处转移,10例(6.76%)对侧甲状腺转移,56例(37.84%)颈部淋巴结转移；1年、3年、5年生存率依次为97.3%、93.2%、83.8%；年龄、病理床分期、病理类型、淋巴结转移、远处转移以及周围组织侵犯均是影响临床预后的重要因素(P<0.05)。结论女性甲状腺癌存在病理分期晚、病理分型差、淋巴结转移、远处转移及局部侵犯率高等不良预后因素,早期影像学检查对临床治疗具有指导意义。
目的：探討女性甲狀腺癌的病理特點以及預後影響因素。方法整群選取2008年1月—2012年1月,該院收治的女性甲狀腺癌患者148例,迴顧分析其臨床病理特點以及預後影響因素。結果病理檢查顯示133例(89.9%)甲狀腺乳頭狀癌(PTC),6例(4.1%)為濾泡狀癌(FTC),3例(2.0%)為髓樣癌(MTC),6例(4.1%)為未分化癌(ATC)；病理分期Ⅰ~Ⅱ期佔45.3%,Ⅲ~Ⅳ期佔54.7%；27例(18.24%)為週圍組織侵犯,9例(6.1%)為遠處轉移,10例(6.76%)對側甲狀腺轉移,56例(37.84%)頸部淋巴結轉移；1年、3年、5年生存率依次為97.3%、93.2%、83.8%；年齡、病理床分期、病理類型、淋巴結轉移、遠處轉移以及週圍組織侵犯均是影響臨床預後的重要因素(P<0.05)。結論女性甲狀腺癌存在病理分期晚、病理分型差、淋巴結轉移、遠處轉移及跼部侵犯率高等不良預後因素,早期影像學檢查對臨床治療具有指導意義。
목적：탐토녀성갑상선암적병리특점이급예후영향인소。방법정군선취2008년1월—2012년1월,해원수치적녀성갑상선암환자148례,회고분석기림상병리특점이급예후영향인소。결과병리검사현시133례(89.9%)갑상선유두상암(PTC),6례(4.1%)위려포상암(FTC),3례(2.0%)위수양암(MTC),6례(4.1%)위미분화암(ATC)；병리분기Ⅰ~Ⅱ기점45.3%,Ⅲ~Ⅳ기점54.7%；27례(18.24%)위주위조직침범,9례(6.1%)위원처전이,10례(6.76%)대측갑상선전이,56례(37.84%)경부림파결전이；1년、3년、5년생존솔의차위97.3%、93.2%、83.8%；년령、병리상분기、병리류형、림파결전이、원처전이이급주위조직침범균시영향림상예후적중요인소(P<0.05)。결론녀성갑상선암존재병리분기만、병리분형차、림파결전이、원처전이급국부침범솔고등불량예후인소,조기영상학검사대림상치료구유지도의의。
Objective To investigate the pathological features and the prognostic factors of female patients with thyroid cancer. Methods 148 cases of female patients with thyroid cancer in our hospital between January 2008 and January 2012 were collected, the clinical and pathological characteristics and prognostic factors were reviewed and analyzed. Results Pathological examination showed that 133 cases (89.9%) were papillary thyroid cancer (PTC), 6 patients (4.1%) were follicular cancer (FTC), 3 cases (2.0%) were medullary cancer (MTC), 6 patients (4.1%) were undifferentiated cancer (ATC);Pathological stageⅠ-Ⅱperiod accounted for 45.3%,Ⅲ -Ⅳstage accounted for 54.7%;27 cases (18.24%) of surrounding tissue invasion, 9 cases (6.1%) of distant metastases, 10 cases (6.76%) of contralateral thyroid metastases, 56 cases (37.84%) of cervical lymph node metastasis; 1-year, 3-year, 5-year survival rates were 97.3%, 93.2%, 83.8%; age, pathological bed staging, histological type, lymph node metastasis, distant metastasis and surrounding tissue invasion were the mportant clinical prognostic factors (P<0.05). Conclusion Female patients with thyroid cancer have adverse prognostic factors of Late staging, pathological type differential, high lymph node metastasis, distant metastasis and local invasion rate, early imaging has important guiding significance for clinical treatment.
