中外医疗
中外醫療
중외의료
CHINA FOREIGN MEDICAL TREATMENT
2015年
23期
12-13
,共2页
健脾燥湿法%瑞舒伐他汀钙%高脂血症
健脾燥濕法%瑞舒伐他汀鈣%高脂血癥
건비조습법%서서벌타정개%고지혈증
Strengthening-spleen and drying-damp method%Rosuvastatin Calcium%Hyperlipidemia
目的：研究健脾燥湿法联合瑞舒伐他汀钙治疗高血脂症的临床效果。方法将整群选取的该院2012年8月—2014年9月收治的84例患者以随机数表法分为观察组与对照组,均42例,观察组采取自拟健脾燥湿方联合瑞舒伐他汀钙治疗,对照组仅采取瑞舒伐他汀钙治疗,比较两组临床疗效、治疗前后血脂指标(TC、TG、LDL-C、HDL-C)水平变化及不良反应发生率。结果观察组治疗总有效率为95.24%与对照组76.19%比较较高,对比差异有统计学意义(P﹤0.05)；治疗后两组TC、TG、LDL-C较治疗前显著下降,HDL-C显著升高,观察组TC、TG、LDL-C分别为(5.64±0.82) mmol/L、(2.01±0.25) mmol/L、(2.60±0.94) mmol/L与对照组(6.31±0.74) mmol/L、(2.25±0.51) mmol/L、(2.75±0.71) mmol/L比较较低,差异有统计学意义(P﹤0.05),HDL-C两组分别为(3.21±1.03) mmol/L、(2.75±0.71) mmol/L,观察组较高,差异有统计学意义(P﹤0.05)；观察组1例胃部不适,对照组无不良反应出现,两组比较差异无统计学意义(χ2=1.012,P﹥0.05)。结论健脾燥湿法联合瑞舒伐他汀钙治疗高血脂症效果显著,可显著改善患者血脂指标,优于单一西药治疗,具有较好的临床应用价值。
目的：研究健脾燥濕法聯閤瑞舒伐他汀鈣治療高血脂癥的臨床效果。方法將整群選取的該院2012年8月—2014年9月收治的84例患者以隨機數錶法分為觀察組與對照組,均42例,觀察組採取自擬健脾燥濕方聯閤瑞舒伐他汀鈣治療,對照組僅採取瑞舒伐他汀鈣治療,比較兩組臨床療效、治療前後血脂指標(TC、TG、LDL-C、HDL-C)水平變化及不良反應髮生率。結果觀察組治療總有效率為95.24%與對照組76.19%比較較高,對比差異有統計學意義(P﹤0.05)；治療後兩組TC、TG、LDL-C較治療前顯著下降,HDL-C顯著升高,觀察組TC、TG、LDL-C分彆為(5.64±0.82) mmol/L、(2.01±0.25) mmol/L、(2.60±0.94) mmol/L與對照組(6.31±0.74) mmol/L、(2.25±0.51) mmol/L、(2.75±0.71) mmol/L比較較低,差異有統計學意義(P﹤0.05),HDL-C兩組分彆為(3.21±1.03) mmol/L、(2.75±0.71) mmol/L,觀察組較高,差異有統計學意義(P﹤0.05)；觀察組1例胃部不適,對照組無不良反應齣現,兩組比較差異無統計學意義(χ2=1.012,P﹥0.05)。結論健脾燥濕法聯閤瑞舒伐他汀鈣治療高血脂癥效果顯著,可顯著改善患者血脂指標,優于單一西藥治療,具有較好的臨床應用價值。
목적：연구건비조습법연합서서벌타정개치료고혈지증적림상효과。방법장정군선취적해원2012년8월—2014년9월수치적84례환자이수궤수표법분위관찰조여대조조,균42례,관찰조채취자의건비조습방연합서서벌타정개치료,대조조부채취서서벌타정개치료,비교량조림상료효、치료전후혈지지표(TC、TG、LDL-C、HDL-C)수평변화급불량반응발생솔。결과관찰조치료총유효솔위95.24%여대조조76.19%비교교고,대비차이유통계학의의(P﹤0.05)；치료후량조TC、TG、LDL-C교치료전현저하강,HDL-C현저승고,관찰조TC、TG、LDL-C분별위(5.64±0.82) mmol/L、(2.01±0.25) mmol/L、(2.60±0.94) mmol/L여대조조(6.31±0.74) mmol/L、(2.25±0.51) mmol/L、(2.75±0.71) mmol/L비교교저,차이유통계학의의(P﹤0.05),HDL-C량조분별위(3.21±1.03) mmol/L、(2.75±0.71) mmol/L,관찰조교고,차이유통계학의의(P﹤0.05)；관찰조1례위부불괄,대조조무불량반응출현,량조비교차이무통계학의의(χ2=1.012,P﹥0.05)。결론건비조습법연합서서벌타정개치료고혈지증효과현저,가현저개선환자혈지지표,우우단일서약치료,구유교호적림상응용개치。
Objective To study the clinical effect of strengthening-spleen and drying-damp method combined with Rosuvastatin Calcium in the treatment of hyperlipidemia. Methods 84 patients admitted in our hospital from August 2012 to September 2014 were divided into the observation group and the control group by the random number table method with 42 cases in each group. The observation group was treated by self-made strengthening-spleen and drying-damp method combined with Rosuvastatin Cal-cium, and the control group was treated by Rosuvastatin Calcium only. The clinical efficacy, changes of levels of blood lipid index-es(TC, TG, LDL-C, HDL-C) and the incidence of adverse reactions before and after treatment were compared between the two groups. Results The overall response rate was much higher in the observation group than in the control group(95.24%vs 76.19%), the difference between the two groups was statistically significant (P<0.05). After treatment, compared with before treatment, the TC, TG and LDL-C levels decreased but HDL-C level increased significantly in both groups. Compared with the control group, the observation group had much lower TC level [(5.64±0.82) mmol/L vs (6.31±0.74) mmol/L], obviously lower TG level [(2.01±0.25) mmol/L vs (2.25±0.51) mmol/L], significantly lower LDL-C level[(2.60±0.94) mmol/L vs (2.75±0.71) mmol/L](P<0.05). The obser-vation group had much higher HDL-C level than the control group[(3.21±1.03) mmol/L vs (2.75±0.71) mmol/L] (P<0.05). 1 patient in the observation group had stomach discomfort, while no patient had adverse reactions in the control group, the difference be-tween the two groups was not statistically significant(χ2=1.012, P>0.05). Conclusion For the treatment of hyperlipidemia, strength-ening-spleen and drying-damp method combined with Rosuvastatin Calcium has better effect than single western-drug therapy, which can significantly improve the levels of blood lipid indexes with good clinical application value.
