CAJ | 학술논문

目的：研究全髋关节置换后预防静脉血栓使用的利伐沙班与依诺肝素的近期疗效及安全性。方法整群选取2014年3月-2015年1月该院收治的84例初次全髋关节置换手术的病例，随机对照分为利伐沙班组42例，依诺肝素组42例。观察术后有无发生非致死性 PE事件、深静脉血栓、死亡事件，术中及术后输血率和出血量。结果利伐沙班组的深静脉血栓（deep venous thrombosis，DVT）出现了10例，依诺肝素组的DVT出现了9例，在两组患者中都没有发生肺栓塞及PE事件，两组患者的DVT发病率差异无统计学意义（χ2=0.204, P=0.651）。两组患者围手术期的隐性失血量、输血率及总失血量差异无统计学意义（P>0.05），安全性类似。结论利伐沙班预防THA术后 VTE与依诺肝素无明显差异，且利伐沙班较伊诺肝素安全性更高。
목적：연구전관관절치환후예방정맥혈전사용적리벌사반여의낙간소적근기료효급안전성。방법정군선취2014년3월-2015년1월해원수치적84례초차전관관절치환수술적병례，수궤대조분위리벌사반조42례，의낙간소조42례。관찰술후유무발생비치사성 PE사건、심정맥혈전、사망사건，술중급술후수혈솔화출혈량。결과리벌사반조적심정맥혈전（deep venous thrombosis，DVT）출현료10례，의낙간소조적DVT출현료9례，재량조환자중도몰유발생폐전새급PE사건，량조환자적DVT발병솔차이무통계학의의（χ2=0.204, P=0.651）。량조환자위수술기적은성실혈량、수혈솔급총실혈량차이무통계학의의（P>0.05），안전성유사。결론리벌사반예방THA술후 VTE여의낙간소무명현차이，차리벌사반교이낙간소안전성경고。
Objective To study the prevention of venous thromboembolism after total hipreplacement with the advantages of cutting shaaban and in accordance with the presence of heparin in the near future curative effect and safety of selection. Methods March 2014 to January 2015, our hospital 84 cases of primary total hip replacement surgery, randomizedinto the cutting team 42 cases, in accordance with the heparin group of 42 cases.To observe the postoperative presence of nonfatal PE events, deep vein thrombosis, deaths, intraoperative and postoperative blood transfusion rate and the blood loss. Results Benefit fellingsand shift of deep vein thrombosis (deep venous thrombosis, DVT) in 10 cases, in accordance with DVT appeared 9 cases, heparin group, didn't happen in the two groups of patients with pulmonary embolism and PE events, there were no significant difference on twogroups of patients with DVT incidence(χ2=0.204,P=0.204).Two groups of patients with perioperative hidden blood loss, transfusion rate and total blood loss there was no significantdifference(P>0.05), and security. Conclusion The laval shaaban THA postoperative VTEprevention and in accordance with heparin has no obvious difference.And the cut shaaban is eno heparin security is higher.