CAJ | 학술논문

目的：探讨血乳酸、降钙素原（PCT）及C反应蛋白（CRP）在肺炎患者中的应用价值。方法整群选取2013年6月-2014年6月应用免疫荧光分析法测定85例老年肺部感染（肺炎组）患者及80例健康体检者（对照组）血清PCT水平，应用全自动化生化分析仪测定两组血乳酸，应用散射比浊法测定两组血清CRP。结果观察组血乳酸、PCT、CRP水平显著高于对照组，差异有统计学意义（P<0.05）。与存活组相比，死亡组血乳酸、PCT、CRP水平较高，差异有统计学意义（P<0.05）。经受试者特异曲线（ROC）分析显示，血乳酸、PCT、CRP联合检测时灵敏性、特异性、阳性预测值、阴性预测值高于各单项检测（P<0.05）。结论血乳酸、PCT、CRP水平可作为老年肺炎患者病情预后的评价指标。通过联合检测可提高血乳酸、PCT、CRP的在老年肺炎中的应用价值。
목적：탐토혈유산、강개소원（PCT）급C반응단백（CRP）재폐염환자중적응용개치。방법정군선취2013년6월-2014년6월응용면역형광분석법측정85례노년폐부감염（폐염조）환자급80례건강체검자（대조조）혈청PCT수평，응용전자동화생화분석의측정량조혈유산，응용산사비탁법측정량조혈청CRP。결과관찰조혈유산、PCT、CRP수평현저고우대조조，차이유통계학의의（P<0.05）。여존활조상비，사망조혈유산、PCT、CRP수평교고，차이유통계학의의（P<0.05）。경수시자특이곡선（ROC）분석현시，혈유산、PCT、CRP연합검측시령민성、특이성、양성예측치、음성예측치고우각단항검측（P<0.05）。결론혈유산、PCT、CRP수평가작위노년폐염환자병정예후적평개지표。통과연합검측가제고혈유산、PCT、CRP적재노년폐염중적응용개치。
Objective To investigate application value of blood lactate (BLA), procalcitionin (PCT) and C-reactive protein (CRP) in elderly pneumonia. Methods Between June 2013 and June 2014, 85 elderly patients with pulmonary infection (observation group) and 80 healthy patients (control group) underwent determination of the levels of serum PCT, BLA and CRP using immunofluores-cence assay, automatic biochemical analyzer and scattering turbidimetry respectively. Results The levels of serum PCT, BLA and CRP were higher in the observation group than in the control group with statistically significant differences, P<0.05. Compared with those treated successfully, the levels of serum PCT, BLA and CRP were higher in the patients who died at last, and the dif-ferences were statistically significant, P<0.05. ROC analysis showed that combined detection of PCT, BLA and CRP can provide higher sensitivity, specificity, positive predictive value, and negative predictive value than individual detection, P<0.05. Conclu-sion Combined detection of PCT, BLA and CRP has higher application value in elderly pneumonia, while can indicate their prog-nosis.