中外医疗
中外醫療
중외의료
China Foreign Medical Treatment
2015年
24期
22-23,26
,共3页
原发性高血压%血压晨峰%颈动脉粥样硬化
原髮性高血壓%血壓晨峰%頸動脈粥樣硬化
원발성고혈압%혈압신봉%경동맥죽양경화
Essential hypertension%Morning blood pressure surge%Carotid artery atherosclerosis
目的：分析原发性高血压患者血压晨峰与颈动脉粥样硬化的关系。方法随机选取该院2013年1月-2014年12月收治的原发性高血压患者130例，对患者实施24 h动态血压监测（24 h ABPM），观察患者血压变化，根据患者血压情况，分为A组54例患者为清晨血压高峰和B组76例为无清晨血压高峰，并测定患者颈动脉内膜-中膜厚度（ICA-IMT）和颈总动脉厚度（CCA-IMT）。结果A组24hSBP、白昼SBP、夜间SBP、晨峰SBP、CCA-IMT、CAB-IMT及ICA-IMT显著高于B组，A组颈动脉粥样硬化斑块形成率66.7%较B组42.1%高，颈动脉斑块Ⅱ级、Ⅲ级发生率较B组高，差异有统计学意义（P<0.05）。结论原发性高血压晨峰患者存在明显的颈动脉粥样硬化，可促进颈动脉粥样硬化的形成。
目的：分析原髮性高血壓患者血壓晨峰與頸動脈粥樣硬化的關繫。方法隨機選取該院2013年1月-2014年12月收治的原髮性高血壓患者130例，對患者實施24 h動態血壓鑑測（24 h ABPM），觀察患者血壓變化，根據患者血壓情況，分為A組54例患者為清晨血壓高峰和B組76例為無清晨血壓高峰，併測定患者頸動脈內膜-中膜厚度（ICA-IMT）和頸總動脈厚度（CCA-IMT）。結果A組24hSBP、白晝SBP、夜間SBP、晨峰SBP、CCA-IMT、CAB-IMT及ICA-IMT顯著高于B組，A組頸動脈粥樣硬化斑塊形成率66.7%較B組42.1%高，頸動脈斑塊Ⅱ級、Ⅲ級髮生率較B組高，差異有統計學意義（P<0.05）。結論原髮性高血壓晨峰患者存在明顯的頸動脈粥樣硬化，可促進頸動脈粥樣硬化的形成。
목적：분석원발성고혈압환자혈압신봉여경동맥죽양경화적관계。방법수궤선취해원2013년1월-2014년12월수치적원발성고혈압환자130례，대환자실시24 h동태혈압감측（24 h ABPM），관찰환자혈압변화，근거환자혈압정황，분위A조54례환자위청신혈압고봉화B조76례위무청신혈압고봉，병측정환자경동맥내막-중막후도（ICA-IMT）화경총동맥후도（CCA-IMT）。결과A조24hSBP、백주SBP、야간SBP、신봉SBP、CCA-IMT、CAB-IMT급ICA-IMT현저고우B조，A조경동맥죽양경화반괴형성솔66.7%교B조42.1%고，경동맥반괴Ⅱ급、Ⅲ급발생솔교B조고，차이유통계학의의（P<0.05）。결론원발성고혈압신봉환자존재명현적경동맥죽양경화，가촉진경동맥죽양경화적형성。
Objective To analyze the relationship between morning blood pressure surge and carotid artherosclerosis in patients with essential hypertension. Methods 130 patients with essential hypertension admitted to our hospital between January 2013 and December 2014 were randomly selected. 24h ambulatory blood pressure monitoring (24h ABPM) was performed on them to observe the change of their blood pressure, and according to blood pressure they were divided into morning blood pressure surge group with 54 patients and without morning blood pressure surge group with 76 patients to determine the intimal medial thickness of in-ternal carotid arteries (ICA-IMT) and common carotid intimal medial thickness (CCA-IMT). Results 24h systolic blood pressure (SBP), daytime SBP, night-time SBP, morning peak SBP, CCA-IMT, CAB-IMT and ICA-IMT, as well as formation rate of carotid artery atherosclerotic plaque and occurrence of plaque in grade II, Ⅲ were higher in the group A than in the group B, and the differences were statistically significant, P<0.05. Conclusion Morning blood pressure surge can promote the formation of carotid artherosclerosis which always exists in patients with essential hypertension.
