中外医疗
中外醫療
중외의료
China Foreign Medical Treatment
2015年
28期
142-144
,共3页
脑卒中%抑郁症%西酞普兰
腦卒中%抑鬱癥%西酞普蘭
뇌졸중%억욱증%서태보란
Stroke%Depression%Citalopram
目的 研究抗抑郁治疗对卒中后抑郁患者的临床疗效.方法 随机选取该院从2013年1月—2014年12月收治的脑卒中急性期60例患者随机分成两组,对照组30例给予常规治疗,未给予抗抑郁药物. 治疗组30例即在常规治疗上加用西酞普兰20 mg, qd口服.在治疗前,治疗后2周、4周、8周分别用汉密顿抑郁量表评分(HAMD)进行疗效评定. 结果 治疗组4W后HAMD均分为(16.7±3.22)分,治疗组8W后HAMD均分为(11.7±2.21)分,症状显著改善,治疗前后症状对比差异具有统计学意义(P<0.01). 同时与同一时期对照组比较,抑郁症状改善的差异有统计学意义. 结论 对脑卒中患者进行PSD及时筛查、尽早药物治疗,能改善患者的预后.
目的 研究抗抑鬱治療對卒中後抑鬱患者的臨床療效.方法 隨機選取該院從2013年1月—2014年12月收治的腦卒中急性期60例患者隨機分成兩組,對照組30例給予常規治療,未給予抗抑鬱藥物. 治療組30例即在常規治療上加用西酞普蘭20 mg, qd口服.在治療前,治療後2週、4週、8週分彆用漢密頓抑鬱量錶評分(HAMD)進行療效評定. 結果 治療組4W後HAMD均分為(16.7±3.22)分,治療組8W後HAMD均分為(11.7±2.21)分,癥狀顯著改善,治療前後癥狀對比差異具有統計學意義(P<0.01). 同時與同一時期對照組比較,抑鬱癥狀改善的差異有統計學意義. 結論 對腦卒中患者進行PSD及時篩查、儘早藥物治療,能改善患者的預後.
목적 연구항억욱치료대졸중후억욱환자적림상료효.방법 수궤선취해원종2013년1월—2014년12월수치적뇌졸중급성기60례환자수궤분성량조,대조조30례급여상규치료,미급여항억욱약물. 치료조30례즉재상규치료상가용서태보란20 mg, qd구복.재치료전,치료후2주、4주、8주분별용한밀돈억욱량표평분(HAMD)진행료효평정. 결과 치료조4W후HAMD균분위(16.7±3.22)분,치료조8W후HAMD균분위(11.7±2.21)분,증상현저개선,치료전후증상대비차이구유통계학의의(P<0.01). 동시여동일시기대조조비교,억욱증상개선적차이유통계학의의. 결론 대뇌졸중환자진행PSD급시사사、진조약물치료,능개선환자적예후.
Objective To investigate the effects of anti-depression theraputics on post-stroke depression. Methods From 2013 January to December 2014, 60 patients with acute stroke were randomly divided into two groups, not given antidepressants. Treat-ment group of 30 patients in the conventional therapy that citalopram 20mg qd orally. Before treatment and after 2, 4 and 8 weeks, efficacy were assessed using the Hamilton Depression Rating Scale (HAMD). Results The treatment group after 4W HAMD were divided into (16.7 ±3.22) points, 8W HAMD after treatment group were divided into (11.7 ±2.21) points, a significant improvement in symptoms, the symptoms contrast difference was significant (P<0.01) before and after treatment. While the difference compared with the same period in the control group, depressive symptoms were significantly improved. Conclusion Stroke patients PSD time-ly screening, early drug treatment can improve the prognosis.
