中外医疗
中外醫療
중외의료
China Foreign Medical Treatment
2015年
28期
145-146
,共2页
齐拉西酮%丙戊酸钠%精神分裂症
齊拉西酮%丙戊痠鈉%精神分裂癥
제랍서동%병무산납%정신분렬증
Ziprasidone%Sodium valproate%Schizophrenia
目的 探讨齐拉西酮联合丙戊酸钠治疗精神分裂症的临床疗效. 方法 通过对整群选取2011年2月—2015年4月在该院进行治疗的82例精神分裂症患者随机分组,其中对照组患者应用齐拉西酮治疗,实验组患者实施齐拉西酮联合丙戊酸钠治疗. 观察比较两组患者治疗效果、PASS评分和不良反应发生率差异. 结果 实验组患者总有效率明显高于对照组、PASS评分显著改善,差异具有统计学意义(P<0.05),两组患者不良反应发生率差异无统计学意义(P>0.05). 结论 齐拉西酮联合丙戊酸钠治疗精神分裂症可明显提高治疗效果,降低PASS评分,无严重不良反应,其具有安全有效等特点,临床值得推广应用.
目的 探討齊拉西酮聯閤丙戊痠鈉治療精神分裂癥的臨床療效. 方法 通過對整群選取2011年2月—2015年4月在該院進行治療的82例精神分裂癥患者隨機分組,其中對照組患者應用齊拉西酮治療,實驗組患者實施齊拉西酮聯閤丙戊痠鈉治療. 觀察比較兩組患者治療效果、PASS評分和不良反應髮生率差異. 結果 實驗組患者總有效率明顯高于對照組、PASS評分顯著改善,差異具有統計學意義(P<0.05),兩組患者不良反應髮生率差異無統計學意義(P>0.05). 結論 齊拉西酮聯閤丙戊痠鈉治療精神分裂癥可明顯提高治療效果,降低PASS評分,無嚴重不良反應,其具有安全有效等特點,臨床值得推廣應用.
목적 탐토제랍서동연합병무산납치료정신분렬증적림상료효. 방법 통과대정군선취2011년2월—2015년4월재해원진행치료적82례정신분렬증환자수궤분조,기중대조조환자응용제랍서동치료,실험조환자실시제랍서동연합병무산납치료. 관찰비교량조환자치료효과、PASS평분화불량반응발생솔차이. 결과 실험조환자총유효솔명현고우대조조、PASS평분현저개선,차이구유통계학의의(P<0.05),량조환자불량반응발생솔차이무통계학의의(P>0.05). 결론 제랍서동연합병무산납치료정신분렬증가명현제고치료효과,강저PASS평분,무엄중불량반응,기구유안전유효등특점,림상치득추엄응용.
Objective To evaluate the clinical efficacy of ziprasidone in the treatment of schizophrenia combined with valproate. Methods By February 2011 to April 2015 in our hospital for treatment of 82 cases of patients with schizophrenia randomized con-trol group in which patients ziprasidone treatment, the experimental group was treated ziprasidone joint valproate sodium treatment. To compare the two groups of patient outcomes, PASS scores and differences in the incidence of adverse reactions. Results The experimental group was significantly higher total efficiency, PASS scores improved significantly, the difference was statistically sig-nificant (P<0.05), the incidence of adverse reactions was not statistically significant (P>0.05). Conclusion Ziprasidone joint val-proate therapy can significantly improve the treatment of schizophrenia, reduce PASS scores, no serious adverse reactions, it is safe and effective features, clinical worth promoting.