CAJ | 학술논문

目的：探讨D-二聚体联合纤维蛋白原检测在急性肺栓塞患者中诊断的应用价值。方法随机选取2012年12月-2014年12月该院收治的急性肺栓塞患者60例作为观察组和正常者60例作为对照组，比较两组血浆中D-二聚体和纤维蛋白原的水平。结果观察组血浆D-二聚体和Fg单独检测水平均高于对照组，差异有统计学意义(P<0.05)；观察组血浆中D-二聚体和Fg单独及联合检出率均高于对照组，差异有统计学意义(P<0.05)；D-二聚体和Fg联合检测的的灵敏度和特异性分别为95.0%和70.0%，明显高于D-二聚体和Fg单独检测，差异有统计学意义(P<0.05)。结论血浆D-二聚体联合Fg检测有助于提高急性肺栓塞患者检出率，对于急性肺栓塞患者的诊断具有重要临床价值。
목적：탐토D-이취체연합섬유단백원검측재급성폐전새환자중진단적응용개치。방법수궤선취2012년12월-2014년12월해원수치적급성폐전새환자60례작위관찰조화정상자60례작위대조조，비교량조혈장중D-이취체화섬유단백원적수평。결과관찰조혈장D-이취체화Fg단독검측수평균고우대조조，차이유통계학의의(P<0.05)；관찰조혈장중D-이취체화Fg단독급연합검출솔균고우대조조，차이유통계학의의(P<0.05)；D-이취체화Fg연합검측적적령민도화특이성분별위95.0%화70.0%，명현고우D-이취체화Fg단독검측，차이유통계학의의(P<0.05)。결론혈장D-이취체연합Fg검측유조우제고급성폐전새환자검출솔，대우급성폐전새환자적진단구유중요림상개치。
Objective To investigate the application value of D-dimer combined with Fg in patients with acute pulmonary embolism. Methods The 60 patients with acute pulmonary embolism in our hospital from December 2014 to December 2012 were selected as the observation group, the 60 healthy volunteers were selected as the control group, the level of plasma D-dimer and Fg of two groups were compared. Results The levels of plasma D-dimer and Fg in the observation group were higher than the control group, the difference was statistically significant (P<0.05). The alone and combined detection rate of D-dimer and Fg in the observation group was higher than the control group, the difference was statistically significant (P<0.05). The sensitivity and specificity of D-dimer and Fg were 95% and 70%, significantly higher than D-dimer and Fg alone detection, the difference was statistically significant (P<0.05). Conclusion The detection of plasma D-dimer combined with Fg is helpful to improve the detection rate of patients with acute pulmonary embolism, which has important clinical value in the diagnosis of acute pulmonary embolism.