中外医疗
中外醫療
중외의료
China Foreign Medical Treatment
2015年
31期
80-81,89
,共3页
高危前列腺癌%局限性%手术治疗%预后
高危前列腺癌%跼限性%手術治療%預後
고위전렬선암%국한성%수술치료%예후
High-risk prostate cancer%Limitations%Surgical treatment%Prognosis
目的：通过采用不同手术方式治疗局限性高危前列腺癌，探讨其最佳手术治疗方式。方法整群选择该院2009年3月-2012年3月收治的76例局限性高位前列腺癌患者，根据患者意愿的手术治疗方式分为腹腔镜组(42例)和植入组(34例)，腹腔镜组采用常规的腹腔镜下根治性前列腺切除术，植入组患者行125I放射性粒子植入术，对两组患者的手术情况、术后并发症及1、3年的生存率进行观察和统计。结果植入组患者的手术时间、术中出血量、住院时间及胃肠道恢复时间均显著少于腹腔镜组(P<0.05)，而两组患者术后的尿失禁及性功能障碍发生率和1、3年的中位生存率比较则差异无统计学意义(P>0.05)。结论在局限性高危前列腺癌手术中采用125I放射性粒子植入术较常规的腹腔镜下根治性前列腺切除术，能够显著改善患者的术中情况，对胃肠道功能影响较小。
目的：通過採用不同手術方式治療跼限性高危前列腺癌，探討其最佳手術治療方式。方法整群選擇該院2009年3月-2012年3月收治的76例跼限性高位前列腺癌患者，根據患者意願的手術治療方式分為腹腔鏡組(42例)和植入組(34例)，腹腔鏡組採用常規的腹腔鏡下根治性前列腺切除術，植入組患者行125I放射性粒子植入術，對兩組患者的手術情況、術後併髮癥及1、3年的生存率進行觀察和統計。結果植入組患者的手術時間、術中齣血量、住院時間及胃腸道恢複時間均顯著少于腹腔鏡組(P<0.05)，而兩組患者術後的尿失禁及性功能障礙髮生率和1、3年的中位生存率比較則差異無統計學意義(P>0.05)。結論在跼限性高危前列腺癌手術中採用125I放射性粒子植入術較常規的腹腔鏡下根治性前列腺切除術，能夠顯著改善患者的術中情況，對胃腸道功能影響較小。
목적：통과채용불동수술방식치료국한성고위전렬선암，탐토기최가수술치료방식。방법정군선택해원2009년3월-2012년3월수치적76례국한성고위전렬선암환자，근거환자의원적수술치료방식분위복강경조(42례)화식입조(34례)，복강경조채용상규적복강경하근치성전렬선절제술，식입조환자행125I방사성입자식입술，대량조환자적수술정황、술후병발증급1、3년적생존솔진행관찰화통계。결과식입조환자적수술시간、술중출혈량、주원시간급위장도회복시간균현저소우복강경조(P<0.05)，이량조환자술후적뇨실금급성공능장애발생솔화1、3년적중위생존솔비교칙차이무통계학의의(P>0.05)。결론재국한성고위전렬선암수술중채용125I방사성입자식입술교상규적복강경하근치성전렬선절제술，능구현저개선환자적술중정황，대위장도공능영향교소。
Objective To investigate the best surgical treatment for high-risk localized prostate cancer by treating this dis-ease with different surgical procedures. Methods 76 patients with localized high-risk prostate cancer admitted to our hospi-tal from March 2009 and March 2012 were included and divided, according to the surgical procedures selected by them-selves, into laparoscopic group (n=42) and implantation group (n=34). The laparoscopic group adopted conventional laparo-scopic radical prostatectomy, while the implantation group underwent 125I radioactive particle implantation. The indicators of the patients in the operation, postoperative complication, and survival rate at 1 and 3 years postoperatively were observed and recorded in the two groups. Results The operation duration, intraoperative blood loss, lengthy of hospital stay, and re-covery time of gastrointestinal function were all significantly less in the laparoscopic group than in the implantation group, P<0.05, but in terms of the rate of postoperative urinary incontinence and sexual dysfunction of the patients, as well as their median survival rate at 1 and 3 years postoperatively, no statistically significant difference can be found between the two groups, P>0.05. Conclusion Compared with conventional laparoscopic radical prostatectomy,125I radioactive particle implan-tation in the treatment of patients with high-risk localized prostate cancer can more remarkably improve their intraoperative situation and has less negative impact on their gastrointestinal function.
