CAJ | 학술논문

目的：分析研究百草枯中毒患者预后相关因素以及急救措施。方法整群选取2013年10月-2014年12月在该院接收的患有百草枯中毒的患者一共有72例，对72例患者采取及时、有效的急救措施，对其急救效果以及影像预后因素给予分析研究。结果72例患者采取血液灌流以后的血浆百草枯浓度明显低于血液灌流之前(P<0.05)；血液灌流以后的SOD活力明显高于血液灌流之前(P<0.05)；病死组的首次血液灌流时间要比存活组晚(P<0.05)；病死组患者服用百草枯剂量明显高于存活组(P<0.05)；病死组患者就诊时间明显要比存活组晚(P<0.05)；病死组并发症发生率明显低于存活组(P<0.05)；就诊时间以及首次血液灌流时间越早，服用毒物剂量越小，其生存时间就越长。结论百草枯中毒患者的预后受到各种各样因素的影响，可是最为主要的因素包括有首次血液灌流时间、服用毒物剂量以及就诊时间三种。所以，百草枯中毒一定要早期采取治疗，使临床病死率明显减少，使患者生存质量明显提高，具有临床推广价值。
목적：분석연구백초고중독환자예후상관인소이급급구조시。방법정군선취2013년10월-2014년12월재해원접수적환유백초고중독적환자일공유72례，대72례환자채취급시、유효적급구조시，대기급구효과이급영상예후인소급여분석연구。결과72례환자채취혈액관류이후적혈장백초고농도명현저우혈액관류지전(P<0.05)；혈액관류이후적SOD활력명현고우혈액관류지전(P<0.05)；병사조적수차혈액관류시간요비존활조만(P<0.05)；병사조환자복용백초고제량명현고우존활조(P<0.05)；병사조환자취진시간명현요비존활조만(P<0.05)；병사조병발증발생솔명현저우존활조(P<0.05)；취진시간이급수차혈액관류시간월조，복용독물제량월소，기생존시간취월장。결론백초고중독환자적예후수도각충각양인소적영향，가시최위주요적인소포괄유수차혈액관류시간、복용독물제량이급취진시간삼충。소이，백초고중독일정요조기채취치료，사림상병사솔명현감소，사환자생존질량명현제고，구유림상추엄개치。
Objective To analyze and study the emergency treatment and factors affecting the prognosis of paraquat poison-ing patients. Methods 72 cases with paraquat poisoning admitted in our hospital from October 2013 to December 2014 were selected. All the patients were given timely effective emergency treatment. And the results of emergency treatment and fac-tors affecting the prognosis were analyzed and studied. Results After blood perfusion, the plasma paraquat concentration was much lower than that before blood perfusion(P<0.05);the activity of SOD was significantly higher than that before blood per-fusion (P<0.05). The first blood perfusion time of the death group was later than that of the survival group (P<0.05). Patients in the death group took much more paraquat dose than those in the survival group (P<0.05). The survival group visited hospital much earlier than the death group (P<0.05). The death group had much lower incidence of complications than the survival group (P<0.05). The earlier visiting time and first blood perfusion time, and smaller paraquat dose, the longer survival time would be. Conclusion Many factors can affect the prognosis of paraquat poisoning, and the main factors are first blood per-fusion time, dose of paraquat and visiting time. Paraquat poisoning needs to be treated early, which can significantly reduce the mortality, improve the quality of life with the value of clinical promotion.