中外医疗
中外醫療
중외의료
CHINA FOREIGN MEDICAL TREATMENT
2009年
21期
63-64
,共2页
流感疫苗%免疫效果%抗体
流感疫苗%免疫效果%抗體
류감역묘%면역효과%항체
Flu vaccine%Immunity effect%Antibody
目的 了解病毒全颗粒灭活流感疫苗与病毒裂解流感疫苗对中国健康人群的血清学免疫效果,为流感疫苗选择使用提供科学依据.方法 接种两种疫苗于2组健康人群,在免疫后不同时间检测其抗体滴度,计算其抗体保护率和抗体阳性率.结果 除乙型抗体几何平均滴度(GMT)在免疫后150d2组差异有统计学意义外(t=2.127 P<0.05),其余各检测期,各型抗体GMT、抗体保护率及阳性率两种疫苗之间的差异无统计学意义.结论 病毒全颗粒灭活流感疫苗与病毒裂解流感疫苗血清学免疫效果基本相同.
目的 瞭解病毒全顆粒滅活流感疫苗與病毒裂解流感疫苗對中國健康人群的血清學免疫效果,為流感疫苗選擇使用提供科學依據.方法 接種兩種疫苗于2組健康人群,在免疫後不同時間檢測其抗體滴度,計算其抗體保護率和抗體暘性率.結果 除乙型抗體幾何平均滴度(GMT)在免疫後150d2組差異有統計學意義外(t=2.127 P<0.05),其餘各檢測期,各型抗體GMT、抗體保護率及暘性率兩種疫苗之間的差異無統計學意義.結論 病毒全顆粒滅活流感疫苗與病毒裂解流感疫苗血清學免疫效果基本相同.
목적 료해병독전과립멸활류감역묘여병독렬해류감역묘대중국건강인군적혈청학면역효과,위류감역묘선택사용제공과학의거.방법 접충량충역묘우2조건강인군,재면역후불동시간검측기항체적도,계산기항체보호솔화항체양성솔.결과 제을형항체궤하평균적도(GMT)재면역후150d2조차이유통계학의의외(t=2.127 P<0.05),기여각검측기,각형항체GMT、항체보호솔급양성솔량충역묘지간적차이무통계학의의.결론 병독전과립멸활류감역묘여병독렬해류감역묘혈청학면역효과기본상동.
Objiective To study virus entire pellet deactivation flu vaccine and the viral decomposition fluvaccine to the Chinese healthy crowd's serology immunity effect,hope to provide the scientific basis for flu vaccine choice.Methods Vaccinates these two kind of vaccines separately in two groups of healthy crowds, the different time examines its antibody titer after the immunity, calculates its antibody protection ratio and the antibody masculine gender rate. Results There has no statistics significance difference between two kinds of vaccine antibody geometric mean titer (GMT),antibody protection ratioor masculine gender rate inall various detection periods except B antibody GMT in the immunity latter 150 days (t=2.127,P<0.05).Conclusion Virus entire pellet deactivation flu vaccine and viral decomposition flu vaccine have same effect of serology immunity.