CAJ | 학술논문

目的：从紫菜中提取多糖，然后与Fe(Ⅲ)合成一种新型的营养补铁剂。方法：合成紫菜多糖Fe(Ⅲ)配合物(PTC)，并测定其相应的理化性质。结果：PTC的水溶液中不存在游离的Fe(Ⅲ)，表明Fe(Ⅲ)与紫菜多糖形成了稳定的配合物。PTC在pH 7.34的生理盐水中不沉、不水解；动力学实验表明PTC中的Fe(Ⅲ)易被还原。经红外光谱分析，PTC是以β-(FeOOH)n为微核，紫菜多糖在核表面形成化合物。结论：PTC有望成为较好生物利用度的营养型补铁剂。
목적：종자채중제취다당，연후여Fe(Ⅲ)합성일충신형적영양보철제。방법：합성자채다당Fe(Ⅲ)배합물(PTC)，병측정기상응적이화성질。결과：PTC적수용액중불존재유리적Fe(Ⅲ)，표명Fe(Ⅲ)여자채다당형성료은정적배합물。PTC재pH 7.34적생리염수중불침、불수해；동역학실험표명PTC중적Fe(Ⅲ)역피환원。경홍외광보분석，PTC시이β-(FeOOH)n위미핵，자채다당재핵표면형성화합물。결론：PTC유망성위교호생물이용도적영양형보철제。
OBJECTIVE:Porphyra polysaccharide isolated from Porphyra,then iron(Ⅲ)-porphyra polysaccharide(PTC)complex was synthesized with FeCl3 and porphyra polysaccharied.METHODS:A new kind of iron-supplementary drug has been prepared.RESULTS:Experiment showed that porphyra polysaccharied iron(Ⅲ)complex was able to be dissolve in water and its solution assumed neutral,and this complex has no precipitate at pH to 11,therefore,this complex was very stable.The investigation by infrared spectra indicated that the structure of porphyra polysaccharide iron(Ⅲ)had been an interfacial complex with β-（FeOOH）ncore.Because this complex was not precipitated and dissociated at the physiological pH=7.34.CONCLUSION:Porphyra polysaccharide iron(Ⅲ) complex was able to become higher bioavailability and nutrition iron-supplementary.