CAJ | 학술논문

目的:探讨血浆同型半胱氨酸(Hcy)与急性脑梗死近期预后的关系.方法:测定291例急性脑梗死患者空腹Hcy,并以此结果将患者分为Hcy升高者为观察组和正常者为对照组,对两组患者神经功能缺损、日常生活能力及脑梗死的复发情况进行追踪观察.结果:观察组和对照组在入院时、发病14d神经功能缺损和日常生活能力评分差异无显著性(P>0.05),在发病后30 d、180 d观察组神经功能缺损评分显著高于对照组,生活能力评分显著低于正常组,1年内脑梗死的复发率显著高于正常组(P<0.05).结论:高Hcy血症对脑梗死患者的恢复存在不良影响,并且使复发的危险性增加.
목적:탐토혈장동형반광안산(Hcy)여급성뇌경사근기예후적관계.방법:측정291례급성뇌경사환자공복Hcy,병이차결과장환자분위Hcy승고자위관찰조화정상자위대조조,대량조환자신경공능결손、일상생활능력급뇌경사적복발정황진행추종관찰.결과:관찰조화대조조재입원시、발병14d신경공능결손화일상생활능력평분차이무현저성(P>0.05),재발병후30 d、180 d관찰조신경공능결손평분현저고우대조조,생활능력평분현저저우정상조,1년내뇌경사적복발솔현저고우정상조(P<0.05).결론:고Hcy혈증대뇌경사환자적회복존재불량영향,병차사복발적위험성증가.
Objective:To study the relationship between plasma homocysteine(Hcy) and short term prognosis of acute cerebral in-farction. Methods:We measureed the plasma Hcy of 291 patients with acute cerebral infarction, then we divided the patients into H hcy (homocysteinemia) group and normal group on the basis of the examming outcome. We observed the neural deficit ability of daily life and recurrence rate of cerebral infarction. Results:There was no statistical difference between the 2 groups in the neural deficit score and a-bility score of daily life on the admission and 14 d of onset (P>0.05). On 30 d,180 d,the neural deficit score of the H hcy group respec-tively was significantly higher than that of the normal group, the ability score of daily life was opposite (P<0.05), and the recurrence rate of cerebral infarction of H hey group was also significantly higher than that of the normal group(P<0.01). Conclusion:H hcy is harmful to the rehabilitation of the patients with acute cerebral infarction, and increases recurrence risk of cerebral infarction.