CAJ | 학술논문

用荧光法研究了氟罗沙星对牛血清白蛋白的荧光猝灭现象，根据荧光猝灭双倒数图计算了氟罗沙星与牛血清白蛋白之间的结合常数，根据Föster能量传递原理计算出氟罗沙星在牛血清白蛋白上的结合位置，并根据热力学参数确定了氟罗沙星与牛血清白蛋白之间的作用力类型.
용형광법연구료불라사성대우혈청백단백적형광졸멸현상，근거형광졸멸쌍도수도계산료불라사성여우혈청백단백지간적결합상수，근거Föster능량전체원리계산출불라사성재우혈청백단백상적결합위치，병근거열역학삼수학정료불라사성여우혈청백단백지간적작용력류형.
A fluorescence method is used to study the fluorescence quenchingof bovine serum albumin by its interaction with fleroxacin. The interaction association constants of bovine serum albumin and fleroxacin are determined from a double reciprocal Lineweaver-Burk plot. According to the Fster dipole-dipole energy transfer, the distance to be measured between the fleroxacin and tryptophane is 4.37 nm. From thermodynamical coordination it can be judged that the binding power between fleroxacin and bovine serum albumin is static electric power.